| Literature DB >> 33106262 |
James M Byrne1,2, Ursula Waack3,2, Edward A Weinstein3, Abhay Joshi4, Simone M Shurland3, Dmitri Iarikov3, Jürgen B Bulitta5, Binh An Diep6, Tina Guina7, William W Hope8, Matthew B Lawrenz9, Alexander J Lepak10, Brian M Luna11, Lynn Miesel12, Andrew J Phipps13, Thomas J Walsh14, William Weiss15, Thushi Amini3, John J Farley3.
Abstract
The U.S. Food and Drug Administration (FDA) hosted a public workshop entitled "Advancing Animal Models for Antibacterial Drug Development" on 5 March 2020. The workshop mainly focused on models of pneumonia caused by Pseudomonas aeruginosa and Acinetobacter baumannii The program included discussions from academic investigators, industry, and U.S. government scientists. The potential use of mouse, rabbit, and pig models for antibacterial drug development was presented and discussed.Entities:
Keywords: FDA; animal models; antibacterial; antibiotics; drug development; humanized dose; pneumonia; regulatory; workshop
Year: 2020 PMID： 33106262 PMCID： PMC7927847 DOI： 10.1128/AAC.01983-20
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191