Literature DB >> 33101679

Efficacy of pulsed-xenon ultraviolet light on reduction of Mycobacterium fortuitum.

Thomas W Huber1, Emma Brackens1, Piyali Chatterjee1, Frank C Villamaria1, Lauren E Sisco2, Marjory D Williams1, John David Coppin1, Hosoon Choi1, Chetan Jinadatha2,3,4.   

Abstract

OBJECTIVES: Hospitals and healthcare facilities rely largely on isolation and environmental disinfection to prevent transmission of pathogens. The use of no-touch technology is an accepted practice for environmental decontamination in medical care facilities, but little has been published about the effect of ultraviolet light generated by a portable pulsed-xenon device use on Mycobacteria. We used Mycobacterium fortuitum which is more resistant to ultraviolet radiation and less virulent than Mycobacterium tuberculosis, to determine the effectiveness of portable pulsed-xenon devices on Mycobacterium in a laboratory environment.
METHODS: To determine the effectiveness of pulsed-xenon devices, we measured the bactericidal effect of pulsed-xenon devices on Mycobacterium fortuitum.
RESULTS: In five separate experiments irradiating an average of 106 organisms, the mean (standard deviation) log-kill at 5 min was 3.98 (0.60), at 10 min was 4.96 (0.42), and at 15 min was 5.64 (0.52).
CONCLUSIONS: Our results demonstrate that using pulsed-xenon devices is a highly effective modality to reduce microbial counts with this relatively ultraviolet germicidal irradiation-resistant mycobacterium in a time-dependent manner.
© The Author(s) 2020.

Entities:  

Keywords:  Mycobacterium fortuitum; Ultraviolet disinfection; pulsed-xenon ultraviolet

Year:  2020        PMID: 33101679      PMCID: PMC7550950          DOI: 10.1177/2050312120962372

Source DB:  PubMed          Journal:  SAGE Open Med        ISSN: 2050-3121


  17 in total

1.  Impact of pulsed xenon ultraviolet light on hospital-acquired infection rates in a community hospital.

Authors:  Pedro G Vianna; Charles R Dale; Sarah Simmons; Mark Stibich; Carmelo M Licitra
Journal:  Am J Infect Control       Date:  2015-12-09       Impact factor: 2.918

2.  Effectiveness of an ultraviolet-C disinfection system for reduction of healthcare-associated pathogens.

Authors:  Jui-Hsuan Yang; Un-In Wu; Huei-Min Tai; Wang-Huei Sheng
Journal:  J Microbiol Immunol Infect       Date:  2017-09-18       Impact factor: 4.399

3.  Response of Mycobacteria to ultraviolet light radiation.

Authors:  H L David
Journal:  Am Rev Respir Dis       Date:  1973-11

4.  Germicidal effect of ultraviolet irradiation on paper contaminated with mycobacteria.

Authors:  T W Huber; R A Reddick; G P Kubica
Journal:  Appl Microbiol       Date:  1970-02

5.  Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations.

Authors:  Ayon Chakraborty; Sandip Kumar Nandi; Alok Kumar Panda; Pinaki Prasad Mahapatra; Sourav Giri; Ashis Biswas
Journal:  Int J Biol Macromol       Date:  2018-07-25       Impact factor: 6.953

6.  Is the pulsed xenon ultraviolet light no-touch disinfection system effective on methicillin-resistant Staphylococcus aureus in the absence of manual cleaning?

Authors:  Chetan Jinadatha; Frank C Villamaria; Marcos I Restrepo; Nagaraja Ganachari-Mallappa; I-Chia Liao; Eileen M Stock; Laurel A Copeland; John E Zeber
Journal:  Am J Infect Control       Date:  2015-05-23       Impact factor: 2.918

7.  Inactivation of environmental mycobacteria by free chlorine and UV.

Authors:  Eun-Sook Lee; Tae-Ho Yoon; Mok-Young Lee; Sun-Hee Han; Jong-Ok Ka
Journal:  Water Res       Date:  2009-11-10       Impact factor: 11.236

8.  Epidemiology of Rapidly Growing Mycobacteria Bloodstream Infections.

Authors:  Michelle A Rodriguez-Coste; Ioana Chirca; Lisa L Steed; Cassandra D Salgado
Journal:  Am J Med Sci       Date:  2016-03       Impact factor: 2.378

Review 9.  'No touch' technologies for environmental decontamination: focus on ultraviolet devices and hydrogen peroxide systems.

Authors:  David J Weber; Hajime Kanamori; William A Rutala
Journal:  Curr Opin Infect Dis       Date:  2016-08       Impact factor: 4.915

10.  The efficacy of vacuum-ultraviolet light disinfection of some common environmental pathogens.

Authors:  Wai Szeto; W C Yam; Haibao Huang; Dennis Y C Leung
Journal:  BMC Infect Dis       Date:  2020-02-11       Impact factor: 3.090

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