| Literature DB >> 33099843 |
Corrine Zarwan1,2, Olivia Diamond3,4, Prudence Lam3,4, Musie S Ghebremichael5, Margaret Lotz3, Abra H Shen6, Sheida Sharifi1,2, Flora Rozhansky7, Teresa Ann Gore8, Susan E Pories3,4.
Abstract
Atypical hyperplasia (AH) and lobular carcinoma in situ (LCIS) are markers for an increased risk of breast cancer, yet outcomes for these diagnoses are not well-documented. In this study, all breast biopsies performed for radiologic abnormalities over a 10-year period were reviewed. Patients with AH or LCIS were followed for an additional 10 years to assess subsequent rates of cancer diagnosis. Long-term follow-up showed that 25 (7.8%) patients with AH and 5 patients with LCIS (5.7%) developed breast cancer over the follow-up period, a lower rate of breast cancer development than predicted by risk models.Entities:
Keywords: atypical ductal hyperplasia; atypical hyperplasia; atypical lobular hyperplasia; breast cancer; lobular carcinoma in situ; risk
Year: 2020 PMID： 33099843 DOI： 10.1111/tbj.14097
Source DB: PubMed Journal: Breast J ISSN： 1075-122X Impact factor: 2.431