| Literature DB >> 33099111 |
Mathieu Fieldes1, Engi Ahmed2, Chloé Bourguignon1, Joffrey Mianné1, Mélanie Martin3, Cécile Arnould3, Isabelle Vachier4, Said Assou1, John De Vos5, Arnaud Bourdin6.
Abstract
Human pluripotent stem cells (hiPSC) are highly valuable tools to model lung development and chronic bronchial diseases. We generated a hiPSC line from a highly characterized 40-year-old healthy male nonsmoking donor. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using integration-free Sendai Virus. The cell line had normal karyotype, expressed pluripotency hallmarks, and differentiated into the three primary germ layers. The reported UHOMi002-A iPSC line may be used as a control to model lung development, study human chronic bronchial diseases and drug testing.Entities:
Mesh:
Substances:
Year: 2020 PMID: 33099111 DOI: 10.1016/j.scr.2020.102037
Source DB: PubMed Journal: Stem Cell Res ISSN: 1873-5061 Impact factor: 2.020