Arun Ganesh1, Yawar J Qadri2, Richard L Boortz-Marx1, Sana M Al-Khatib3, David H Harpole4, Jason N Katz3, Jason I Koontz3,5, Joseph P Mathew1, Neil D Ray1, Albert Y Sun3, Betty C Tong4, Luis Ulloa1,6, Jonathan P Piccini3,7,5, Marat Fudim8,9. 1. Duke Anesthesiology, Duke University, Durham, NC, USA. 2. Emory Anesthesiology, Emory University, Atlanta, GA, USA. 3. Duke Cardiology, Duke University Medical Center, 2301 Erwin Road, Durham, NC, 27710, USA. 4. Cardiothoracic Surgery, Duke University Medical Center, Durham, NC, USA. 5. Duke Center for Atrial Fibrillation, Duke University Medical Center, Duke University, Durham, NC, USA. 6. Center for Perioperative Organ Protection, Department of Anesthesiology, Duke University, Durham, NC, USA. 7. Duke Clinical Research Institute, Durham, NC, USA. 8. Duke Cardiology, Duke University Medical Center, 2301 Erwin Road, Durham, NC, 27710, USA. marat.fudim@dm.duke.edu. 9. Duke Clinical Research Institute, Durham, NC, USA. marat.fudim@dm.duke.edu.
Abstract
PURPOSE OF REVIEW: To highlight the indications, procedural considerations, and data supporting the use of stellate ganglion blockade (SGB) for management of refractory ventricular arrhythmias. RECENT FINDINGS: In patients with refractory ventricular arrhythmias, unilateral or bilateral SGB can reduce arrhythmia burden and defibrillation events for 24-72 h, allowing time for use of other therapies like catheter ablation, surgical sympathectomy, or heart transplantation. The efficacy of SGB appears to be consistent despite the type (monomorphic vs polymorphic) or etiology (ischemic vs non-ischemic cardiomyopathy) of the ventricular arrhythmia. Ultrasound-guided SGB is safe with low risk for complications, even when performed on anticoagulation. SGB is effective and safe and could be considered for patients with refractory ventricular arrhythmias.
PURPOSE OF REVIEW: To highlight the indications, procedural considerations, and data supporting the use of stellate ganglion blockade (SGB) for management of refractory ventricular arrhythmias. RECENT FINDINGS: In patients with refractory ventricular arrhythmias, unilateral or bilateral SGB can reduce arrhythmia burden and defibrillation events for 24-72 h, allowing time for use of other therapies like catheter ablation, surgical sympathectomy, or heart transplantation. The efficacy of SGB appears to be consistent despite the type (monomorphic vs polymorphic) or etiology (ischemic vs non-ischemic cardiomyopathy) of the ventricular arrhythmia. Ultrasound-guided SGB is safe with low risk for complications, even when performed on anticoagulation. SGB is effective and safe and could be considered for patients with refractory ventricular arrhythmias.
Authors: Sophie C Hofferberth; Frank Cecchin; Dan Loberman; Francis Fynn-Thompson Journal: J Thorac Cardiovasc Surg Date: 2013-10-24 Impact factor: 5.209