Simona Di Lascio1, Enrico Tognazzo2, Sara Bigiotti3, Marta Bonollo3, Alberto Costa4, Olivia Pagani5, Francesco Meani6. 1. Oncology Institute of Southern Switzerland - IOSI, Bellinzona, Switzerland; CSSI, Centro di Senologia Della Svizzera Italiana, Ente Ospedaliero Cantonale - EOC, Switzerland. Electronic address: simona.dilascio@eoc.ch. 2. Gynecology and Obstetric Department, Ente Ospedaliero Cantonale - EOC, Lugano, Switzerland. Electronic address: enrico.tognazzo@hcuge.ch. 3. Gynecology and Obstetric Department, Ente Ospedaliero Cantonale - EOC, Lugano, Switzerland. 4. CSSI, Centro di Senologia Della Svizzera Italiana, Ente Ospedaliero Cantonale - EOC, Switzerland; European School of Oncology - ESO, Milano, Italy. 5. European School of Oncology - ESO, Milano, Italy; Interdisciplinary Cancer Service, Hopital Riviera-Chablais, Rennaz, Vaud, Geneva University Hospitals, Switzerland. 6. CSSI, Centro di Senologia Della Svizzera Italiana, Ente Ospedaliero Cantonale - EOC, Switzerland; Gynecology and Obstetric Department, Ente Ospedaliero Cantonale - EOC, Lugano, Switzerland.
Abstract
INTRODUCTION: Risk of breast cancer increases with age and very few data are available in patients older than 89. METHODS: A retrospective analysis on patients aged 89 and older treated between 2008 and 2019 at our certified breast center. The aim was to analyze clinical characteristics, decision-making, treatment, outcomes and open questions regarding this subpopulation for which there is a lack of guidelines. RESULTS: 58 patients included. Tumor characteristics were analyzed, 85% patients underwent surgery of which 44% had a mastectomy. The median follow-up and overall survival were 20 and 76 months, respectively.The median survival of metastatic and non-metastatic patients were 14 and 50 months, respectively. Most patients did not receive any adjuvant treatment and among these 14% had a relapse. CONCLUSIONS: Elderly patients should not be under or over-treated because of their age; they represent a large heterogeneous group deserving a sub-stratification for a better tailored treatment.
INTRODUCTION: Risk of breast cancer increases with age and very few data are available in patients older than 89. METHODS: A retrospective analysis on patients aged 89 and older treated between 2008 and 2019 at our certified breast center. The aim was to analyze clinical characteristics, decision-making, treatment, outcomes and open questions regarding this subpopulation for which there is a lack of guidelines. RESULTS: 58 patients included. Tumor characteristics were analyzed, 85% patients underwent surgery of which 44% had a mastectomy. The median follow-up and overall survival were 20 and 76 months, respectively.The median survival of metastatic and non-metastatic patients were 14 and 50 months, respectively. Most patients did not receive any adjuvant treatment and among these 14% had a relapse. CONCLUSIONS: Elderly patients should not be under or over-treated because of their age; they represent a large heterogeneous group deserving a sub-stratification for a better tailored treatment.