Literature DB >> 33096201

Does a 5-day course of antibiotics in elderly patients with community-acquired pneumonia achieve the established criteria of clinical stability?

C Flateau1, M Dinia2, N Raulet2, S Sayegh3, S Diamantis4, M Jager2.   

Abstract

OBJECTIVE: We aimed to determine the proportion of elderly patients hospitalised for community-acquired pneumonia (CAP) in whom a 5-day antibiotic therapy would achieve clinical stability according to American Thoracic Society (ATS) criteria.
METHODS: Patients aged≥75 years, hospitalised for CAP between November 2018 and August 2019, were analysed retrospectively. The American Thoracic Society (ATS) clinical stability criteria (temperature≤37°C, heart rate≤100/min, respiratory rate≤24/min, systolic blood pressure≥90mmHg, oxygen saturation≥90% in room air) were assessed after five days of antibiotic therapy.
RESULTS: Seventy-five patients (mean age 88 years, 49% requiring oxygen therapy) were included. Six died, and at day 5, 36/69 (52%) fulfilled 4/5 stability criteria. The median duration of treatment was 9 days. In 28 patients (41%), it was ≤7 days.
CONCLUSION: In 52% of elderly patients with CAP, a 5-day treatment regimen resulted in clinical stability.
Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Antibiotic; Community-acquired pneumonia; Elderly; Treatment duration

Year:  2020        PMID: 33096201     DOI: 10.1016/j.medmal.2020.10.015

Source DB:  PubMed          Journal:  Infect Dis Now        ISSN: 2666-9919


  1 in total

1.  Ulinastatin plus biapenem for severe pneumonia in the elderly and its influence on pulmonary function and inflammatory cytokines.

Authors:  Rui Zhang; Jitao Ma; Pengxiao Zheng; Ruirui Zheng; Xu Meng; Yinjia Wang
Journal:  Am J Transl Res       Date:  2021-05-15       Impact factor: 4.060

  1 in total

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