Literature DB >> 33095649

The safety of primary surgical excision of small deep indeterminate musculoskeletal soft tissue masses.

Michèle Calleja1, Qasim Afzaal2, Asif Saifuddin1.   

Abstract

OBJECTIVE: To determine the suitability of primary excision of small indeterminate deep soft tissue masses presenting to a tertiary musculoskeletal oncology service. METHODS AND MATERIALS: Review of all patients referred to a specialist musculoskeletal oncology service over a 20-month period with a deep indeterminate soft tissue mass by non-contrast MRI criteria that was recommended for primary surgical excision due to relatively small size (<30 mm). Data collected included age, gender, site and maximal size of the lesion, and final histological diagnosis for excised lesions.
RESULTS: 85 patients were included, mean lesion size being 12 mm (range 5-29 mm). Primary surgical resection had been undertaken in 69 cases (81.2%) by the conclusion of data collection, 36 males and 33 females with mean age of 45.6 years (range 11-80 years). Of these, 11 cases (15.9%) were non-neoplastic, 53 (76.8%) were benign, 1 (1.4%) was intermediate grade, while 4 (5.8%) were malignant including 3 synovial sarcomas. Two of these were treated with re-excision of the tumour bed showing no residual disease, with no evidence of local recurrence at a mean of 10.7 months post-excision.
CONCLUSION: Primary surgical excision of small deep soft tissue masses that are indeterminate by non-contrast MRI criteria is considered a safe procedure when undertaken in a specialist musculoskeletal oncology service, with only 4 of 69 cases (5.8%) being malignant. ADVANCES IN KNOWLEDGE: Small indeterminate deep soft tissue masses can safely be treated with primary excision in the setting of a specialist musculoskeletal oncology service.

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Year:  2020        PMID: 33095649      PMCID: PMC7774678          DOI: 10.1259/bjr.20200713

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  39 in total

1.  Non-neoplastic conditions presenting as soft-tissue tumours.

Authors:  N Crundwell; P O'Donnell; A Saifuddin
Journal:  Clin Radiol       Date:  2007-01       Impact factor: 2.350

2.  Small Musculoskeletal Soft-Tissue Lesions: US-guided Core Needle Biopsy--Comparative Study of Diagnostic Yields according to Lesion Size.

Authors:  Sang Yoon Kim; Hye Won Chung
Journal:  Radiology       Date:  2015-07-08       Impact factor: 11.105

3.  Characterization of indeterminate soft tissue masses referred for biopsy: What is the added value of contrast imaging at 3.0 tesla?

Authors:  Filippo Del Grande; Shivani Ahlawat; Ty Subhawong; L M Fayad
Journal:  J Magn Reson Imaging       Date:  2016-07-15       Impact factor: 4.813

4.  Usefulness of diffusion-weighted MR imaging for differentiating between benign and malignant superficial soft tissue tumours and tumour-like lesions.

Authors:  Ji Young Jeon; Hye Won Chung; Min Hee Lee; Sang Hoon Lee; Myung Jin Shin
Journal:  Br J Radiol       Date:  2016-02-19       Impact factor: 3.039

Review 5.  Needle tract seeding after percutaneous biopsy of sarcoma: Risk/benefit considerations.

Authors:  David Berger-Richardson; Carol J Swallow
Journal:  Cancer       Date:  2016-11-02       Impact factor: 6.860

Review 6.  Soft Tissue Tumors in Adults: ESSR-Approved Guidelines for Diagnostic Imaging.

Authors:  Iris M Noebauer-Huhmann; Marc-André Weber; Radhesh K Lalam; Siegfried Trattnig; Klaus Bohndorf; Filip Vanhoenacker; Alberto Tagliafico; Carla van Rijswijk; Joan C Vilanova; P Diana Afonso; Martin Breitenseher; Ian Beggs; Philip Robinson; Milko C de Jonge; Christian Krestan; Johan L Bloem
Journal:  Semin Musculoskelet Radiol       Date:  2015-12-22       Impact factor: 1.777

7.  Soft-tissue vascular anomalies: utility of US for diagnosis.

Authors:  H J Paltiel; P E Burrows; H P Kozakewich; D Zurakowski; J B Mulliken
Journal:  Radiology       Date:  2000-03       Impact factor: 11.105

8.  Synovial Sarcoma: A Series of Small Tumors in Active Duty Service Members.

Authors:  Taylor Bates; Erica Kao; Joseph Alderete; Dustin Lybeck
Journal:  Mil Med       Date:  2020-09-18       Impact factor: 1.437

9.  Major-nerve schwannomas versus intramuscular schwannomas.

Authors:  S Shimose; T Sugita; T Kubo; T Matsuo; H Nobuto; K Tanaka; K Arihiro; M Ochi
Journal:  Acta Radiol       Date:  2007-07       Impact factor: 1.990

10.  Development and Validation of Nomograms for Malignancy Prediction in Soft Tissue Tumors Using Magnetic Resonance Imaging Measurements.

Authors:  Ji Hyun Lee; Young Cheol Yoon; Wook Jin; Jang Gyu Cha; Seonwoo Kim
Journal:  Sci Rep       Date:  2019-03-20       Impact factor: 4.379

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