Literature DB >> 33094757

A hydrophilic magnetic MOF for the consecutive enrichment of exosomes and exosomal phosphopeptides.

Ning Zhang1, Nianrong Sun2, Chunhui Deng3.   

Abstract

Hydrophilic Fe3O4@PDA@UIO-66-NH2 is employed to consecutively enrich urinary exosomes and exosomal phosphopeptides through the strong bond between Zr and phosphate groups. The recovery of exosomes reached 95% and 707 phosphopeptides were identified from 255 phosphoproteins via LC-MS/MS. This work will make a great contribution to further functional analysis of exosomes.

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Year:  2020        PMID： 33094757     DOI： 10.1039/d0cc06147f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Exosome-functionalized magnesium-organic framework-based scaffolds with osteogenic, angiogenic and anti-inflammatory properties for accelerated bone regeneration.

Authors:  Yue Kang; Chang Xu; Ling'ao Meng; Xufeng Dong; Min Qi; Daqing Jiang
Journal:  Bioact Mater       Date:  2022-02-18

2.  [Preparation of dual-functional composite magnetic nanomaterials modified with different metals/aptamers and their performance in exosome enrichment].

Authors:  Weibing Zhang; Rui Lu; Lingyi Zhang
Journal:  Se Pu       Date:  2021-10
  2 in total

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