Literature DB >> 33092392

Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography.

Cristina Del-Prado-Sánchez1, Olga Seijas-Leal1, Pablo Gili-Manzanaro1, Juan Ferreiro-López1, Julio Yangüela-Rodilla1, Alfonso Arias-Puente1.   

Abstract

PURPOSE: To study the subfoveal choroidal thickness (SFCT), macular ganglion cell layer (GCL-IPL) and central macular thickness (CMT) in Caucasian children, and to analyze these optical coherence tomography (OCT) parameters depending on the spherical equivalent (SE).
METHODS: Cross-sectional study of SFCT, GCL-IPL, and CMT in Caucasian children, analyzed with spectral-domain OCT Cirrus 5000 and Enhanced-depth imaging technique. Correlation between these three OCT parameters, age, sex, and spherical equivalent was analyzed. The eyes were classified into three groups: group 1 included eyes with SE < 0, group 2 included eyes with SE between 0 and +2.00, and group 3 eyes with SE > +2.00.
RESULTS: Hundred ninety-eight eyes of 121 subjects were studied. The mean age was 9.22 years (range 3-16); 61.1% were female. The mean SFCT was 351.04 ± 84.08 µm, being 310.04 ± 82.84µm in group 1 (n = 62), 373.14 ± 83.16 µm in group 2 (n = 71) and 365.18 ± 73.16 µm in group 3 (n = 65); statistically significant differences were found between groups 2 and 3, compared with group 1. GCL-IPL thickness was significantly thinner (p < 0.001) in group 1, compared with group 3. There were no statistically significant differences between the three groups regarding CMT. Correlation with age, and sex was not found.
CONCLUSIONS: SFCT and GCL-IPL thickness were significantly thinner (p < 0.001) in myopic children when compared with a non-myopic pediatric population. However, it seems that there is not a correlation among the three OCT parameters studied, age and sex, when they are analyzed depending on refractive error.

Entities:  

Keywords:  Amblyopia; Pediatric ophthalmology; optics / refraction / instruments; pathologic myopia; retina; strabismus

Mesh:

Year:  2020        PMID: 33092392     DOI: 10.1177/1120672120965486

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  2 in total

1.  Normative data and repeatability for macular ganglion cell layer thickness in healthy Swedish children using swept source optical coherence tomography.

Authors:  Philip Wolf; Eva Larsson; Hanna Åkerblom
Journal:  BMC Ophthalmol       Date:  2022-03-08       Impact factor: 2.209

2.  Assessment of macular structures and vascular characteristics in highly myopic anisometropia using swept-source optical coherence tomography angiography.

Authors:  Xin Wang; Yanhui Chen; Zhiyang Wang; Haoru Li; Qing He; Hua Rong; Ruihua Wei
Journal:  Front Physiol       Date:  2022-08-15       Impact factor: 4.755

  2 in total

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