| Literature DB >> 33089272 |
Zhenhua Shen1, Ching-Hsuan Tung.
Abstract
An activatable photosensitizer based on methylene blue was developed and validated for its efficacy in the selective killing of γ-glutamyl transpeptidase expressing cells. The 1O2 deactivation via bond breakage, rapid in situ enzymatic photosensitivity conversion, long lysosomal retention, and nucleus relocation collectively contribute to its strong and selective photodynamic effects.Entities:
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Year: 2020 PMID： 33089272 DOI： 10.1039/d0cc05707j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222