Literature DB >> 33088644

Visceral adiposity is associated with the discrepancy between glycated albumin and HbA1c in type 2 diabetes.

Saori Maruo1, Koka Motoyama1, Tomoe Hirota1, Yoshinori Kakutani1, Yuko Yamazaki1, Tomoaki Morioka1, Katsuhito Mori2, Shinya Fukumoto3, Atsushi Shioi4, Tetsuo Shoji4, Masaaki Inaba1, Masanori Emoto1.   

Abstract

AIM: We investigated the association of visceral adiposity with glycated albumin (GA) as well as GA/hemoglobin A1c (HbA1c) in type 2 diabetes.
METHODS: One hundred twenty-three patients (68 males, 55 females) with type 2 diabetes were enrolled in this cross-sectional study. Visceral fat area (VFA) was determined using an abdominal dual bioelectrical impedance analysis (dual BIA) instrument. The relationship of VFA with GA and GA/HbA1c was analyzed.
RESULTS: Simple regression analysis showed that BMI was inversely correlated with GA as well as GA/HbA1c, but not with HbA1c, while VFA had a significant correlation with GA and GA/HbA1c. Furthermore, multiple regression analysis revealed VFA as an independent contributor to GA/HbA1c. These results suggest that visceral adiposity is a primary factor associated with GA and HbA1c level discrepancy in patients with type 2 diabetes.
CONCLUSIONS: GA is a useful indicator for glycemic control, while visceral obesity should also be taken into consideration in type 2 diabetes cases. © The Japan Diabetes Society 2020.

Entities:  

Keywords:  Diabetes mellitus; Glycated albumin; Obesity; Visceral fat area

Year:  2020        PMID： 33088644      PMCID： PMC7538500          DOI： 10.1007/s13340-020-00431-z

Source DB:  PubMed          Journal:  Diabetol Int        ISSN： 2190-1678


  36 in total

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2.  Glycated albumin is low in obese, non-diabetic children.

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3.  Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus.

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4.  Negative association of obesity and its related chronic inflammation with serum glycated albumin but not glycated hemoglobin levels.

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Review 7.  Diabetes control and complications: the role of glycated haemoglobin, 25 years on.

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Authors:  Yuko Yamazaki; Masanori Emoto; Tomoaki Morioka; Naoya Kawano; Eiko Lee; Hiromi Urata; Shoko Tsuchikura; Koka Motoyama; Katsuhito Mori; Shinya Fukumoto; Tetsuo Shoji; Yoshiki Nishizawa; Masaaki Inaba
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9.  Revised equations for estimated GFR from serum creatinine in Japan.

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10.  Visceral Adiposity is Preferentially Associated with Vascular Stiffness Rather than Thickness in Men with Type 2 Diabetes.

Authors:  Hirokazu Morigami; Tomoaki Morioka; Yuko Yamazaki; Satoshi Imamura; Ryutaro Numaguchi; Mariko Asada; Koka Motoyama; Katsuhito Mori; Shinya Fukumoto; Tetsuo Shoji; Masanori Emoto; Masaaki Inaba
Journal:  J Atheroscler Thromb       Date:  2016-03-05       Impact factor: 4.928
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  1 in total

1.  Visceral fat area and body fat percentage measured by bioelectrical impedance analysis correlate with glycometabolism.

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  1 in total

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