Mina Hizal1, Kubra Aykac, Burcu C C Yayla2, Arzu Yilmaz3, Demet Altun4, Habip E Akkaya5, Gulsum I Bayhan6, Aysegul N C Kurt7, Jale Karakaya8, Yasemin Ozsurekci9, Mehmet Ceyhan9. 1. Department of Pediatric Pulmonology, Ankara Training and Research Hospital, University of Health Science, Ankara, Turkey. 2. Department of Pediatric Infectious Disease, Ankara Training and Research Hospital, University of Health Science, Ankara, Turkey. 3. Department of Pediatric, Ankara Training and Research Hospital, University of Health Science, Ankara, Turkey. 4. Department of Pediatrics, Faculty of Medicine, Ufuk University, Ankara, Turkey. 5. Department of Radiology, Ankara Training and Research Hospital, University of Health Science, Ankara, Turkey. 6. Department of Pediatric Infectious Disease, Yenimahalle Training and Educational Hospital, Yildirim Beyazit University, Ankara, Turkey. 7. Department of Pediatrics, Yenimahalle Training and Educational Hospital, Yildirim Beyazit University, Ankara, Turkey. 8. Department of Biostatistics, Hacettepe University, Ankara, Turkey. 9. Department of Pediatric Infectious Disease, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Abstract
BACKGROUND: Lung ultrasound (LUS) has been successfully used in the diagnosis of different pulmonary diseases. Present study design to determine the diagnostic value of LUS in the evaluation of children with novel coronavirus disease 2019 (COVID-19). METHODS AND OBJECTIVES: Prospective multicenter study, 40 children with confirmed COVID-19 were included. LUS was performed to all patients at admission. The chest X-ray and computed tomography (CT) were performed according to the decision of the primary physicians. LUS results were compared with chest X-ray and CT findings and diagnostic performance was determined. RESULTS: Of the 40 children median (range) was 10.5 (0.4-17.8) years. Chest X-ray and LUS were performed on all and chest CT was performed on 28 (70%) patients at the time of diagnosis. Sixteen (40%) patients had no apparent chest CT abnormalities suggestive of COVID-19, whereas 12 (30%) had abnormalities. LUS confirmed the diagnosis of pulmonary involvement in 10 of 12 patients with positive CT findings. LUS demonstrated normal lung patterns among 15 of 16 patients who had normal CT features. The sensitivity and the area under the receiver operating characteristics (ROC) curve (area under the ROC curve) identified by the chest X-ray and LUS tests were compared and statistically significantly different (McNemar's test: p = .016 and p = .001 respectively) detected. Chest X-ray displayed false-negative results for pulmonary involvement in 75% whereas for LUS it was 16.7%. CONCLUSIONS: LUS might be a useful tool in the diagnostic steps of children with COVID-19. A reduction in chest CT assessments may be possible when LUS is used in the initial diagnostic steps for these children.
BACKGROUND: Lung ultrasound (LUS) has been successfully used in the diagnosis of different pulmonary diseases. Present study design to determine the diagnostic value of LUS in the evaluation of children with novel coronavirus disease 2019 (COVID-19). METHODS AND OBJECTIVES: Prospective multicenter study, 40 children with confirmed COVID-19 were included. LUS was performed to all patients at admission. The chest X-ray and computed tomography (CT) were performed according to the decision of the primary physicians. LUS results were compared with chest X-ray and CT findings and diagnostic performance was determined. RESULTS: Of the 40 children median (range) was 10.5 (0.4-17.8) years. Chest X-ray and LUS were performed on all and chest CT was performed on 28 (70%) patients at the time of diagnosis. Sixteen (40%) patients had no apparent chest CT abnormalities suggestive of COVID-19, whereas 12 (30%) had abnormalities. LUS confirmed the diagnosis of pulmonary involvement in 10 of 12 patients with positive CT findings. LUS demonstrated normal lung patterns among 15 of 16 patients who had normal CT features. The sensitivity and the area under the receiver operating characteristics (ROC) curve (area under the ROC curve) identified by the chest X-ray and LUS tests were compared and statistically significantly different (McNemar's test: p = .016 and p = .001 respectively) detected. Chest X-ray displayed false-negative results for pulmonary involvement in 75% whereas for LUS it was 16.7%. CONCLUSIONS:LUS might be a useful tool in the diagnostic steps of children with COVID-19. A reduction in chest CT assessments may be possible when LUS is used in the initial diagnostic steps for these children.
Authors: Andrea Ilundain López de Munain; Cristina Jimenez Veintemilla; Mercedes Herranz Aguirre; Natividad Viguria Sánchez; Beatriz Ramos-Lacuey; María Urretavizcaya-Martínez; Laura Echeverría Esandi; María Del Mar Pina López; Marcos García Howard; Alejandro Fernández-Montero; Laura Moreno-Galarraga Journal: Eur J Radiol Open Date: 2021-03-11
Authors: Damiano D'Ardes; Claudio Tana; Alessandro Salzmann; Fabrizio Ricci; Maria Teresa Guagnano; Maria Adele Giamberardino; Francesco Cipollone Journal: Ann Med Date: 2022-12 Impact factor: 5.348