| Literature DB >> 330851 |
W J Lett, R Ansbacher, B L Davison, W N Otterson.
Abstract
A triple-blind prospective study of women undergoing vaginal hysterectomy was conducted to compare cefazolin, cephaloridine and no antibiotic, Both cefazolin and cephaloridine were given preoperatively, whereas only cephaloridine was given postoperatively. One gram of cefazolin given intramuscularly on call to the operation room was found to be a safe and effective antibiotic for prophylaxis against febrile morbidity. The proper utilization of prophylactic antibiotics seems to be in the immediate preoperative period. The use of antibiotics after the first day of surgery is unnecessary.Entities:
Keywords: Clinical Research; Diseases; Double-blind Studies; Female Sterilization; Gynecologic Surgery; Hysterectomy--complications; Infections; Prospective Studies; Research Methodology; Studies; Surgery; Treatment; Urogenital Surgery
Mesh：
Substances：
Year: 1977 PMID： 330851
Source DB: PubMed Journal: J Reprod Med ISSN： 0024-7758 Impact factor: 0.142