Nurcan Yurtsever Kum1, Rauf Oguzhan Kum1, Tuba Candar2, Deniz Baklaci3, Ismail Guler4, Ihsan Kuzucu5, Kursat Murat Ozcan1, Muge Ozcan1, Huseyin Dere1,6. 1. Department of Otolaryngology, Ankara Sehir Hospital (Formerly Ankara Numune Education and Research Hospital), Ankara, Turkey. 2. Department of Biochemistry, Ufuk University, Ankara, Turkey. 3. ENT Clinic, Kahramankazan State Hospital, Ankara, Turkey. 4. Department of Otolaryngology, Ankara Medipol University, Ankara, Turkey. 5. ENT Clinic, Medisun Cayyolu Hospital, Ankara, Turkey. 6. Department of Otolaryngology, Yıldırım Beyazıt University, Ankara, Turkey.
Abstract
OBJECTIVE: To investigate the serum calprotectin (SCal) levels and neutrophil/lymphocyte ratio (NLR) values in patients with obstructive sleep apnea (OSA). METHODS: Sixty-seven OSA patients and 46 healthy volunteers without any sleep disorders were included in the study. The patient group was divided into three subgroups according to the severity of OSA. The SCal levels and NLR values were compared among subgroups and between the experimental and control groups. RESULTS: The mean SCal level and NLR value were higher in the study group than in the control group (p = 0.002 and p = 0.001, respectively). The SCal levels were significantly higher in patients with severe OSA than in those with moderate and mild OSA (p = 0.004 and p = 0.001, respectively). DISCUSSION: Unlike NLR, the SCal level may inform the severity of OSA and could be used as an indicator for OSA.
OBJECTIVE: To investigate the serum calprotectin (SCal) levels and neutrophil/lymphocyte ratio (NLR) values in patients with obstructive sleep apnea (OSA). METHODS: Sixty-seven OSA patients and 46 healthy volunteers without any sleep disorders were included in the study. The patient group was divided into three subgroups according to the severity of OSA. The SCal levels and NLR values were compared among subgroups and between the experimental and control groups. RESULTS: The mean SCal level and NLR value were higher in the study group than in the control group (p = 0.002 and p = 0.001, respectively). The SCal levels were significantly higher in patients with severe OSA than in those with moderate and mild OSA (p = 0.004 and p = 0.001, respectively). DISCUSSION: Unlike NLR, the SCal level may inform the severity of OSA and could be used as an indicator for OSA.
Authors: Tezcan Kaya; Selçuk Yaylacı; Ahmet Nalbant; İlhan Yıldırım; Havva Kocayiğit; Erdem Çokluk; Mehmet Ramazan Şekeroğlu; Mehmet Köroğlu; Ertuğrul Güçlü Journal: Ir J Med Sci Date: 2021-02-27 Impact factor: 1.568