Literature DB >> 33080269

Commentary: COVID-19 and obesity pandemics converge into a syndemic requiring urgent and multidisciplinary action.

Michael A Hill1, James R Sowers2, Christos S Mantzoros3.   

Abstract

While substantial evidence points towards obesity and associated cardiometabolic disorders being a major factor for poor outcomes in SARS-CoV2 infections (COVID-19), the complexity of the interplay between these two pandemics is becoming apparent. Indeed, as previously defined, this interaction between obesity and COVID-19 represents a 'syndemic' that requires both current and ongoing attention. At a mechanistic level the chronic inflammatory environment of obesity predisposes to life threatening events such as cytokine storm and enhanced coagulopathy. Obesity and its management are affected by diverse factors manifested at societal, educational, racial, and nutritional levels. A multidisciplinary approach is required to manage obese and type 2 diabetic patients, not only during the current COVID-19 crisis, but to decrease the growing burden of cardiometabolic disease and associated cardiovascular complications impacting future viral pandemics. Further, this syndemic has highlighted disparities in healthcare which need to be addressed to achieve equality in health outcomes in patients infected with COVID-19.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Year:  2020        PMID: 33080269     DOI: 10.1016/j.metabol.2020.154408

Source DB:  PubMed          Journal:  Metabolism        ISSN: 0026-0495            Impact factor:   8.694


  8 in total

Review 1.  Body mass index is just a number: Conflating riskiness and unhealthiness in discourse on body size.

Authors:  Iliya Gutin
Journal:  Sociol Health Illn       Date:  2021-06-04

Review 2.  A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the Pandemic.

Authors:  Chris R Triggle; Devendra Bansal; Hong Ding; Md Mazharul Islam; Elmoubashar Abu Baker Abd Farag; Hamad Abdel Hadi; Ali A Sultan
Journal:  Front Immunol       Date:  2021-02-26       Impact factor: 7.561

Review 3.  Understanding the Co-Epidemic of Obesity and COVID-19: Current Evidence, Comparison with Previous Epidemics, Mechanisms, and Preventive and Therapeutic Perspectives.

Authors:  Maria Dalamaga; Gerasimos Socrates Christodoulatos; Irene Karampela; Natalia Vallianou; Caroline M Apovian
Journal:  Curr Obes Rep       Date:  2021-04-28

4.  Prevention of Cardiovascular Burden in COVID-19 Patients Suffering from Familial Hypercholesterolemia: A Global Challenge.

Authors:  Alpo Vuorio; Petri T Kovanen; Raul D Santos; Frederick Raal
Journal:  Cardiol Ther       Date:  2021-11-17

Review 5.  Obesity, Hypovitaminosis D, and COVID-19: the Bermuda Triangle in Public Health.

Authors:  Irene Karampela; Natalia Vallianou; Faidon Magkos; Caroline M Apovian; Maria Dalamaga
Journal:  Curr Obes Rep       Date:  2022-04-07

6.  Rethinking COVID-19 and Beyond: Prevention, Remedies, and Recovery.

Authors:  Philip B Maffetone; Paul B Laursen
Journal:  Front Public Health       Date:  2022-02-23

Review 7.  Management of hypertension in patients with COVID-19: Implication of angiotensin-converting enzyme 2.

Authors:  Guang-Hong Jia; James R Sowers
Journal:  Cardiol Plus       Date:  2021-12-30

8.  COVID-19 Pandemic Impact on Trajectories in Cardiometabolic Health, Physical Activity, and Functioning Among Adults from the 2006-2020 Health and Retirement Study.

Authors:  Hind A Beydoun; May A Beydoun; Rana S Gautam; Brook T Alemu; Jordan Weiss; Sharmin Hossain; Alan B Zonderman
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2022-07-05       Impact factor: 6.591

  8 in total

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