Literature DB >> 33079080

Rhamnose modified bovine serum albumin as a carrier protein promotes the immune response against sTn antigen.

Han Lin1, Haofei Hong, Jinfeng Wang, Chen Li, Zhifang Zhou, Zhimeng Wu.   

Abstract

Rhamnose and sTn antigen were co-conjugated to bovine serum albumin (BSA), a weakly immunogenic carrier protein, for cancer vaccine development. The immune responses against sTn have been significantly augmented with the involvement of Rha-specific antibodies to enhance antigen uptake.

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Year:  2020        PMID: 33079080     DOI: 10.1039/d0cc05263a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Synthetic Antibody-Rhamnose Cluster Conjugates Show Potent Complement-Dependent Cell Killing by Recruiting Natural Antibodies.

Authors:  Chong Ou; Sunaina Kiran Prabhu; Xiao Zhang; Guanghui Zong; Qiang Yang; Lai-Xi Wang
Journal:  Chemistry       Date:  2022-02-21       Impact factor: 5.236

Review 2.  Rhamnose-Containing Compounds: Biosynthesis and Applications.

Authors:  Siqiang Li; Fujia Chen; Yun Li; Lizhen Wang; Hongyan Li; Guofeng Gu; Enzhong Li
Journal:  Molecules       Date:  2022-08-20       Impact factor: 4.927

  2 in total

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