Literature DB >> 33077648

Bacteriophage AB-SA01 Cocktail in Combination with Antibiotics against MRSA-VISA Strain in an In Vitro Pharmacokinetic/Pharmacodynamic Model.

Razieh Kebriaei1, Katherine L Lev1, Kyle C Stamper1, Susan M Lehman2, Sandra Morales2, Michael J Rybak3,4,5.   

Abstract

This study aimed to test the efficacy of bacteriophage-antibiotic combinations (BACs) in vitro in 24-h time-kill settings and in ex vivo simulated endocardial vegetation (SEV) pharmacokinetic/pharmacodynamic models for 96 h. BACs prevented the development of bacteriophage resistance, while some bacteriophage resistance emerged in bacteriophage-alone treatments. In addition, BACs resulted in an enhancement of bacterial eradication in SEV models. Our findings support the potential activity of BAC therapy for combating serious methicillin-resistant Staphylococcus aureus (MRSA) infections.
Copyright © 2020 American Society for Microbiology.

Entities:  

Keywords:  bacteriophage; combination; infective endocarditis

Year:  2020        PMID： 33077648      PMCID： PMC7927802          DOI： 10.1128/AAC.01863-20

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  Genome of staphylococcal phage K: a new lineage of Myoviridae infecting gram-positive bacteria with a low G+C content.

Authors:  S O'Flaherty; A Coffey; R Edwards; W Meaney; G F Fitzgerald; R P Ross
Journal:  J Bacteriol       Date:  2004-05       Impact factor: 3.490

Review 2.  Evolutionary Rationale for Phages as Complements of Antibiotics.

Authors:  Clara Torres-Barceló; Michael E Hochberg
Journal:  Trends Microbiol       Date:  2016-01-17       Impact factor: 17.079

3.  In vitro pharmacodynamics of vancomycin and cefazolin alone and in combination against methicillin-resistant Staphylococcus aureus.

Authors:  Mao Hagihara; Dora E Wiskirchen; Joseph L Kuti; David P Nicolau
Journal:  Antimicrob Agents Chemother       Date:  2011-10-17       Impact factor: 5.191

4.  Enumeration of bacteriophages using the small drop plaque assay system.

Authors:  Amanda Mazzocco; Thomas E Waddell; Erika Lingohr; Roger P Johnson
Journal:  Methods Mol Biol       Date:  2009

Review 5.  Phage Therapy in the Postantibiotic Era.

Authors:  Fernando L Gordillo Altamirano; Jeremy J Barr
Journal:  Clin Microbiol Rev       Date:  2019-01-16       Impact factor: 26.132

6.  Dalbavancin Alone and in Combination with Ceftaroline against Four Different Phenotypes of Staphylococcus aureus in a Simulated Pharmacodynamic/Pharmacokinetic Model.

Authors:  Razieh Kebriaei; Seth A Rice; Kyle C Stamper; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2019-03-27       Impact factor: 5.191

7.  Comparison of a rabbit model of bacterial endocarditis and an in vitro infection model with simulated endocardial vegetations.

Authors:  E Hershberger; E A Coyle; G W Kaatz; M J Zervos; M J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

8.  Safety of bacteriophage therapy in severe Staphylococcus aureus infection.

Authors:  Aleksandra Petrovic Fabijan; Ruby C Y Lin; Josephine Ho; Susan Maddocks; Nouri L Ben Zakour; Jonathan R Iredell
Journal:  Nat Microbiol       Date:  2020-02-17       Impact factor: 17.745

9.  Influence of Inoculum Effect on the Efficacy of Daptomycin Monotherapy and in Combination with β-Lactams against Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions.

Authors:  Razieh Kebriaei; Seth A Rice; Kavindra V Singh; Kyle C Stamper; An Q Dinh; Rafael Rios; Lorena Diaz; Barbara E Murray; Jose M Munita; Truc T Tran; Cesar A Arias; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2018-07-27       Impact factor: 5.191

10.  Different bacteriophage resistance mechanisms in Streptococcus salivarius subsp. thermophilus.

Authors:  D Larbi; B Decaris; J M Simonet
Journal:  J Dairy Res       Date:  1992-08       Impact factor: 1.904
View more
  5 in total

Review 1.  Phage-Antibiotic Therapy as a Promising Strategy to Combat Multidrug-Resistant Infections and to Enhance Antimicrobial Efficiency.

Authors:  Chengxi Liu; Qixuan Hong; Rachel Yoon Kyung Chang; Philip Chi Lip Kwok; Hak-Kim Chan
Journal:  Antibiotics (Basel)       Date:  2022-04-25

Review 2.  Bacteriophage Therapy for Critical and High-Priority Antibiotic-Resistant Bacteria and Phage Cocktail-Antibiotic Formulation Perspective.

Authors:  Gursneh Kaur; Ritika Agarwal; Rakesh Kumar Sharma
Journal:  Food Environ Virol       Date:  2021-06-12       Impact factor: 2.778

3.  Eradication of Biofilm-Mediated Methicillin-Resistant Staphylococcus aureus Infections In Vitro: Bacteriophage-Antibiotic Combination.

Authors:  Razieh Kebriaei; Katherine L Lev; Rahi M Shah; Kyle C Stamper; Dana J Holger; Taylor Morrisette; Ashlan J Kunz Coyne; Susan M Lehman; Michael J Rybak
Journal:  Microbiol Spectr       Date:  2022-03-29

4.  Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis.

Authors:  Jonathan Save; Yok-Ai Que; José M Entenza; Camille Kolenda; Frédéric Laurent; Grégory Resch
Journal:  J Am Heart Assoc       Date:  2022-01-19       Impact factor: 6.106

Review 5.  Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome.

Authors:  Christian Johann Lerche; Franziska Schwartz; Marie Theut; Emil Loldrup Fosbøl; Kasper Iversen; Henning Bundgaard; Niels Høiby; Claus Moser
Journal:  Front Cell Dev Biol       Date:  2021-06-18
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.