Literature DB >> 3307621

Improved sensitivity in assays for binding of novel beta-lactam antibiotics to penicillin-binding proteins of Escherichia coli.

K Bush, S A Smith, S Ohringer, S K Tanaka, D P Bonner.   

Abstract

Tigemonam and temocillin, but not aztreonam, bound to penicillin-binding proteins (PBPs) 1a and 3 of Escherichia coli with apparent improved affinity when challenged with benzylpenicillin at lowered temperatures. Half times for deacylation of the tigemonam-PBP complexes were shorter than were those of the corresponding aztreonam-PBP complexes. The implications of the routine testing of PBP affinities are discussed.

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Year:  1987        PMID： 3307621      PMCID： PMC174917          DOI： 10.1128/AAC.31.8.1271

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography.

Authors:  R A Laskey; A D Mills
Journal:  Eur J Biochem       Date:  1975-08-15

2.  Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.

Authors:  J M Ghuysen; J M Frère; M Leyh-Bouille; M Nguyen-Distèche; J Coyette
Journal:  Biochem J       Date:  1986-04-01       Impact factor: 3.857

3.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  In vivo evaluation of tigemonam, a novel oral monobactam.

Authors:  J M Clark; S J Olsen; D S Weinberg; M Dalvi; R R Whitney; D P Bonner; R B Sykes
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

6.  Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12.

Authors:  B G Spratt
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

Review 7.  Penicillin-sensitive enzymes in peptidoglycan biosynthesis.

Authors:  J M Frère; B Joris
Journal:  Crit Rev Microbiol       Date:  1985       Impact factor: 7.624

8.  Affinity of temocillin for Escherichia coli K-12 penicillin-binding proteins.

Authors:  R Labia; P Baron; J M Masson; G Hill; M Cole
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

9.  Properties of the penicillin-binding proteins of Escherichia coli K12,.

Authors:  B G Spratt
Journal:  Eur J Biochem       Date:  1977-01

10.  In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic.

Authors:  A Imada; M Kondo; K Okonogi; K Yukishige; M Kuno
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191
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  9 in total

1.  Differential responses of Escherichia coli cells expressing cytoplasmic domain mutants of penicillin-binding protein 1b after impairment of penicillin-binding proteins 1a and 3.

Authors:  C Chalut; X Charpentier; M H Remy; J M Masson
Journal:  J Bacteriol       Date:  2001-01       Impact factor: 3.490

2.  BOCILLIN FL, a sensitive and commercially available reagent for detection of penicillin-binding proteins.

Authors:  G Zhao; T I Meier; S D Kahl; K R Gee; L C Blaszczak
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

3.  Differential effect of mutational impairment of penicillin-binding proteins 1A and 1B on Escherichia coli strains harboring thermosensitive mutations in the cell division genes ftsA, ftsQ, ftsZ, and pbpB.

Authors:  F García del Portillo; M A de Pedro
Journal:  J Bacteriol       Date:  1990-10       Impact factor: 3.490

4.  Microtiter plate-based assay for inhibitors of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus.

Authors:  Sudheer Bobba; V K Chaithanya Ponnaluri; Mridul Mukherji; William G Gutheil
Journal:  Antimicrob Agents Chemother       Date:  2011-03-14       Impact factor: 5.191

Review 5.  Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases.

Authors:  I Massova; S Mobashery
Journal:  Antimicrob Agents Chemother       Date:  1998-01       Impact factor: 5.191

6.  Antibacterial characteristics of YTR 830, a sulfone beta-lactamase inhibitor, compared with those of clavulanic acid and sulbactam.

Authors:  F Moosdeen; J D Williams; S Yamabe
Journal:  Antimicrob Agents Chemother       Date:  1988-06       Impact factor: 5.191

Review 7.  Pharmacokinetics and Pharmacodynamics of Temocillin.

Authors:  Kevin Alexandre; Bruno Fantin
Journal:  Clin Pharmacokinet       Date:  2018-03       Impact factor: 6.447

8.  Biochemical characterization of novel tetrahydrofuranyl 1beta-methylcarbapenems: stability to hydrolysis by renal dehydropeptidases and bacterial beta-lactamases, binding to penicillin binding proteins, and permeability properties.

Authors:  Y Yang; R T Testa; N Bhachech; B A Rasmussen; K Bush
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

9.  Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action.

Authors:  Dongxu Sun; Ruslan Tsivkovski; Joe Pogliano; Hannah Tsunemoto; Kirk Nelson; Debora Rubio-Aparicio; Olga Lomovskaya
Journal:  Antimicrob Agents Chemother       Date:  2022-09-14       Impact factor: 5.938
  9 in total

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