Sandeep Mohindra1, Aman Batish2, Manjul Tripathi2, Kaniyappan Nambiyar3, Kirti Gupta3. 1. Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India. sandeepneuro@gmail.com. 2. Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India. 3. Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Abstract
BACKGROUND AND IMPORTANCE: Asymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin. CLINICAL PRESENTATION: The authors report a case of an 18-year-old male patient who developed leiomyosarcoma within chronically neglected cervical myelomeningocele. CONCLUSION: A non-healing ulcer of any aetiology is a bed for carcinogenesis. Neglected myelomeningoceles, for any reason, may convert a benign entity to a malignant pathology. To our best knowledge, this is the first case of a leiomyosarcoma arising de novo from myelomeningocele.
BACKGROUND AND IMPORTANCE: Asymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin. CLINICAL PRESENTATION: The authors report a case of an 18-year-old male patient who developed leiomyosarcoma within chronically neglected cervical myelomeningocele. CONCLUSION: A non-healing ulcer of any aetiology is a bed for carcinogenesis. Neglected myelomeningoceles, for any reason, may convert a benign entity to a malignant pathology. To our best knowledge, this is the first case of a leiomyosarcoma arising de novo from myelomeningocele.
Entities:
Keywords:
Case report; Cervical; Dysraphism; Leiomyosarcoma; Meningomyelocele; Neglect