| Literature DB >> 33070201 |
Codruta Birle1,2, Dana Slavoaca3,4, Maria Balea1,2, Livia Livint Popa1,2, Ioana Muresanu1,2, Emanuel Stefanescu2, Vitalie Vacaras1,2, Constantin Dina5, Stefan Strilciuc1,2, Bogdan Ovidiu Popescu6, Dafin F Muresanu1,2.
Abstract
Cognition is the most complex function of the brain. When exploring the inner workings of cognitive processes, it is crucial to understand the complexity of the brain's dynamics. This paper aims to describe the integrated framework of the cognitive function, seen as the result of organization and interactions between several systems and subsystems. We briefly describe several organizational concepts, spanning from the reductionist hierarchical approach, up to the more dynamic theory of open complex systems. The homeostatic regulation of the mechanisms responsible for cognitive processes is showcased as a dynamic interplay between several anticorrelated mechanisms, which can be found at every level of the brain's organization, from molecular and cellular level to large-scale networks (e.g., excitation-inhibition, long-term plasticity-long-term depression, synchronization-desynchronization, segregation-integration, order-chaos). We support the hypothesis that cognitive function is the consequence of multiple network interactions, integrating intricate relationships between several systems, in addition to neural circuits.Entities:
Keywords: Anticorrelated mechanisms; Cognitive function; Networks; Open complex systems
Mesh:
Year: 2020 PMID: 33070201 DOI: 10.1007/s10072-020-04737-3
Source DB: PubMed Journal: Neurol Sci ISSN: 1590-1874 Impact factor: 3.307