K Marie Douglass1, Katie M Strobel2, Michael Richley1, Thalia Mok1, Annabelle de St Maurice3, Viviana Fajardo2, Andrew T Young4, Rashmi Rao1, Lydia Lee1, Peyman Benharash5, Alison Chu2, Yalda Afshar1. 1. Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles. 2. Division of Neonatology, Department of Pediatrics, University of California, Los Angeles. 3. Division of Infectious Disease, Department of Pediatrics, University of California, Los Angeles. 4. Division of Critical Care, Department of Anesthesia, University of California, Los Angeles. 5. Divison of Cardiac Surgery, Department of Surgery, University of California, Los Angeles.
Abstract
OBJECTIVE: This study aimed to describe two cases of acute respiratory distress syndrome (ARDS) secondary to novel coronavirus disease 2019 (COVID-19) in pregnant women requiring extracorporeal membrane oxygenation (ECMO), and resulting in premature delivery. STUDY DESIGN: The clinical course of two women hospitalized with ARDS due to COVID-19 care in our intensive care (ICU) is summarized; both participants provided consent to be included in this case series. RESULTS: Both women recovered with no clinical sequelae. Neonatal outcomes were within the realm of expected for prematurity with the exception of coagulopathy. There was no vertical transmission to the neonates. CONCLUSION: This case series highlights that ECMO is a feasible treatment in the pregnant woman with severe COVID-19 and that delivery can be performed safely on ECMO with no additional risk to the fetus. While ECMO carries its natural risks, it should be considered a viable option during pregnancy and the postpartum period. KEY POINTS: · COVID-19 may present with a more severe course in pregnancy.. · ECMO may be used in pregnant woman with severe COVID-19.. · Delivery can be performed on ECMO without added fetal risk.. Thieme. All rights reserved.
OBJECTIVE: This study aimed to describe two cases of acute respiratory distress syndrome (ARDS) secondary to novel coronavirus disease 2019 (COVID-19) in pregnant women requiring extracorporeal membrane oxygenation (ECMO), and resulting in premature delivery. STUDY DESIGN: The clinical course of two women hospitalized with ARDS due to COVID-19 care in our intensive care (ICU) is summarized; both participants provided consent to be included in this case series. RESULTS: Both women recovered with no clinical sequelae. Neonatal outcomes were within the realm of expected for prematurity with the exception of coagulopathy. There was no vertical transmission to the neonates. CONCLUSION: This case series highlights that ECMO is a feasible treatment in the pregnant woman with severe COVID-19 and that delivery can be performed safely on ECMO with no additional risk to the fetus. While ECMO carries its natural risks, it should be considered a viable option during pregnancy and the postpartum period. KEY POINTS: · COVID-19 may present with a more severe course in pregnancy.. · ECMO may be used in pregnant woman with severe COVID-19.. · Delivery can be performed on ECMO without added fetal risk.. Thieme. All rights reserved.
Authors: Eloise M Young; Oleia Green; Joel Stewart; Yasmin King; Keelin O'Donoghue; Kate F Walker; Jim G Thornton Journal: Eur J Obstet Gynecol Reprod Biol Date: 2021-12-06 Impact factor: 2.435
Authors: Emily Shih; J Michael DiMaio; John J Squiers; Anita R Krueger; Gary S Schwartz; James Herd; April T Bleich Journal: Am J Obstet Gynecol MFM Date: 2021-11-20