Literature DB >> 33068489

Adoption of faecal immunochemical testing for 2-week-wait colorectal patients during the COVID-19 pandemic: an observational cohort study reporting a new service at a regional centre.

William Maclean1, Chris Limb1, Paul Mackenzie1, Martin B Whyte2, Sally C Benton3, Timothy Rockall1, Iain Jourdan1.   

Abstract

AIM: The COVID-19 pandemic has resulted in the near-complete loss of routine endoscopy services. We describe a major reorganization of service at a regional referral centre (Royal Surrey NHS Foundation Trust) to manage the crisis. Faecal immunochemical testing (FIT) was implemented for triage to make optimum use of limited diagnostic resources. Consultations were switched from face-to-face to telephone. Our aim was to evaluate the impact FIT had on resource allocation and patient diagnoses in the first 3 months of use.
METHOD: All colorectal 2-week-wait patient referrals were posted a pack requesting FIT and notification of telephone consultation. A prepaid envelope was included for return of the samples. At consultation, FIT was incorporated with the presenting symptoms to guide the choice of investigation and triage urgency. FIT ≥10 μg/g was interpreted as positive. Outcome data were collected prospectively and compared with retrospective audit data from prepandemic levels across 3 months.
RESULTS: From 26 March 2020 to 2 July 381 patients were referred who were invited to provide FIT samples and underwent telephone consultations. Three hundred and fifty eight FIT samples were returned (94%). Onward referral for colonoscopy reduced from 62% to 34% (P < 0.001). There were 14 colorectal cancers (CRC) (3.7%) diagnosed, which was not statistically different from the prepandemic level of 3.9% (P = 0.995). Twelve of the 14 patients with a CRC diagnosis had provided samples; all 12 had FIT ≥10 μg/g and were offered fast-track investigations.
CONCLUSIONS: The incorporation of FIT optimized the allocation of limited resources to triage those who required urgent colonic investigation for detecting CRC.
© 2020 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  COVID-19; endoscopy; faecal immunochemical testing; two-week-wait

Year:  2020        PMID: 33068489     DOI: 10.1111/codi.15408

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  7 in total

1.  Prioritisation of lower gastrointestinal endoscopy during the COVID-19 pandemic: outcomes of a novel triage pathway.

Authors:  Thomas Archer; Imran Aziz; Matthew Kurien; Victoria Knott; Alex Ball
Journal:  Frontline Gastroenterol       Date:  2021-06-08

2.  Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology (BSG).

Authors:  Kevin J Monahan; Michael M Davies; Muti Abulafi; Ayan Banerjea; Brian D Nicholson; Ramesh Arasaradnam; Neil Barker; Sally Benton; Richard Booth; David Burling; Rachel Victoria Carten; Nigel D'Souza; James Edward East; Jos Kleijnen; Michael Machesney; Maria Pettman; Jenny Pipe; Lance Saker; Linda Sharp; James Stephenson; Robert Jc Steele
Journal:  Gut       Date:  2022-07-12       Impact factor: 31.793

Review 3.  Impact of the COVID-19 Pandemic on Colorectal Cancer Screening: a Systematic Review.

Authors:  Afrooz Mazidimoradi; Azita Tiznobaik; Hamid Salehiniya
Journal:  J Gastrointest Cancer       Date:  2021-08-18

4.  Recognising Colorectal Cancer in Primary Care.

Authors:  Natalia Calanzani; Aina Chang; Marije Van Melle; Merel M Pannebakker; Garth Funston; Fiona M Walter
Journal:  Adv Ther       Date:  2021-04-17       Impact factor: 3.845

Review 5.  Global Impact of COVID-19 on Colorectal Cancer Screening: Current Insights and Future Directions.

Authors:  Jonathan Kopel; Bojana Ristic; Gregory L Brower; Hemant Goyal
Journal:  Medicina (Kaunas)       Date:  2022-01-10       Impact factor: 2.430

Review 6.  Colorectal Cancer Screening: Impact of COVID-19 Pandemic and Possible Consequences.

Authors:  Isabelle Harber; Dania Zeidan; Muhammad N Aslam
Journal:  Life (Basel)       Date:  2021-11-26

Review 7.  US Cancer Screening Recommendations: Developments and the Impact of COVID-19.

Authors:  Adam Barsouk; Kalyan Saginala; John Sukumar Aluru; Prashanth Rawla; Alexander Barsouk
Journal:  Med Sci (Basel)       Date:  2022-03-01
  7 in total

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