Literature DB >> 33068303

Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations.

Franziska Kluwe1,2, Robin Michelet1, Anna Mueller-Schoell1,2, Corinna Maier2,3, Lena Klopp-Schulze1,2, Madelé van Dyk4, Gerd Mikus1,5, Wilhelm Huisinga3, Charlotte Kloft1.   

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Year:  2020        PMID： 33068303     DOI： 10.1002/cpt.2049

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


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  9 in total

1.  Predicting Antibiotic Effect of Vancomycin Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation: Dense Sampling versus Sparse Sampling.

Authors:  Yong Kyun Kim; Jae Ha Lee; Hang-Jea Jang; Dae Young Zang; Dong-Hwan Lee
Journal:  Antibiotics (Basel)       Date:  2022-05-31

2.  Mechanistic Modelling Identifies and Addresses the Risks of Empiric Concentration-Guided Sorafenib Dosing.

Authors:  Warit Ruanglertboon; Michael J Sorich; Ashley M Hopkins; Andrew Rowland
Journal:  Pharmaceuticals (Basel)       Date:  2021-04-21

3.  Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies.

Authors:  Anna Mueller-Schoell; Lena Klopp-Schulze; Robin Michelet; Madelé van Dyk; Thomas E Mürdter; Matthias Schwab; Markus Joerger; Wilhelm Huisinga; Gerd Mikus; Charlotte Kloft
Journal:  Pharmaceuticals (Basel)       Date:  2021-02-03

4.  A continued learning approach for model-informed precision dosing: Updating models in clinical practice.

Authors:  Corinna Maier; Jana de Wiljes; Niklas Hartung; Charlotte Kloft; Wilhelm Huisinga
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2021-12-27

5.  Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups.

Authors:  Anna Mueller-Schoell; Robin Michelet; Lena Klopp-Schulze; Madelé van Dyk; Thomas E Mürdter; Matthias Schwab; Markus Joerger; Wilhelm Huisinga; Gerd Mikus; Charlotte Kloft
Journal:  Cancers (Basel)       Date:  2021-05-18       Impact factor: 6.639

6.  Combining Therapeutic Drug Monitoring and Pharmacokinetic Modelling Deconvolutes Physiological and Environmental Sources of Variability in Clozapine Exposure.

Authors:  Kenneth H Wills; Stephen J Behan; Michael J Nance; Jessica L Dawson; Thomas M Polasek; Ashley M Hopkins; Madelé van Dyk; Andrew Rowland
Journal:  Pharmaceutics       Date:  2021-12-27       Impact factor: 6.321

7.  Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.

Authors:  Anna M Mc Laughlin; Eduard Schmulenson; Olga Teplytska; Sebastian Zimmermann; Patrick Opitz; Stefanie L Groenland; Alwin D R Huitema; Neeltje Steeghs; Lothar Müller; Stefan Fuxius; Gerald Illerhaus; Markus Joerger; Frank Mayer; Uwe Fuhr; Stefan Holdenrieder; Georg Hempel; Oliver Scherf-Clavel; Ulrich Jaehde; Charlotte Kloft
Journal:  Cancers (Basel)       Date:  2021-12-14       Impact factor: 6.639

8.  Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open-source R package mapbayr.

Authors:  Félicien Le Louedec; Florent Puisset; Fabienne Thomas; Étienne Chatelut; Mélanie White-Koning
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2021-09-08

9.  Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism.

Authors:  Josefine Schulz; Antonia Thomas; Ayatallah Saleh; Gerd Mikus; Charlotte Kloft; Robin Michelet
Journal:  Pharmaceutics       Date:  2022-02-22       Impact factor: 6.321
  9 in total

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