Literature DB >> 33067311

Solar-powered oxygen, quality improvement and child pneumonia deaths: a large-scale effectiveness study.

Trevor Duke1,2, Francis Pulsan2, Doreen Panauwe3, Ilomo Hwaihwanje4, Martin Sa'avu5, Magdalynn Kaupa6, Jonah Karubi6, Eleanor Neal7, Hamish Graham7,8, Rasa Izadnegahdar9, Susan Donath10.   

Abstract

BACKGROUND: Pneumonia is the largest cause of child deaths in low-income countries. Lack of availability of oxygen in small rural hospitals results in avoidable deaths and unnecessary and unsafe referrals.
METHOD: We evaluated a programme for improving reliable oxygen therapy using oxygen concentrators, pulse oximeters and sustainable solar power in 38 remote health facilities in nine provinces in Papua New Guinea. The programme included a quality improvement approach with training, identification of gaps, problem solving and corrective measures. Admissions and deaths from pneumonia and overall paediatric admissions, deaths and referrals were recorded using routine health information data for 2-4 years prior to the intervention and 2-4 years after. Using Poisson regression we calculated incidence rates (IRs) preintervention and postintervention, and incidence rate ratios (IRR).
RESULTS: There were 18 933 pneumonia admissions and 530 pneumonia deaths. Pneumonia admission numbers were significantly lower in the postintervention era than in the preintervention era. The IRs for pneumonia deaths preintervention and postintervention were 2.83 (1.98-4.06) and 1.17 (0.48-1.86) per 100 pneumonia admissions: the IRR for pneumonia deaths was 0.41 (0.24-0.71, p<0.005). There were 58 324 paediatric admissions and 2259 paediatric deaths. The IR for child deaths preintervention and postintervention were 3.22 (2.42-4.28) and 1.94 (1.23-2.65) per 100 paediatric admissions: IRR 0.60 (0.45-0.81, p<0.005). In the years postintervention period, an estimated 348 lives were saved, at a cost of US$6435 per life saved and over 1500 referrals were avoided.
CONCLUSIONS: Solar-powered oxygen systems supported by continuous quality improvement can be achieved at large scale in rural and remote hospitals and health care facilities, and was associated with reduced child deaths and reduced referrals. Variability of effectiveness in different contexts calls for strengthening of quality improvement in rural health facilities. TRIAL REGISTRATION NUMBER: ACTRN12616001469404. © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Entities:  

Keywords:  health services research; mortality

Year:  2020        PMID: 33067311     DOI: 10.1136/archdischild-2020-320107

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  5 in total

1.  The impact of pulse oximetry on diagnosis, management and outcomes of acute febrile illness in low-income and middle-income countries: a systematic review.

Authors:  Rusheng Chew; Meiwen Zhang; Arjun Chandna; Yoel Lubell
Journal:  BMJ Glob Health       Date:  2021-11

2.  Oxygen systems strengthening as an intervention to prevent childhood deaths due to pneumonia in low-resource settings: systematic review, meta-analysis and cost-effectiveness.

Authors:  Felix Lam; Angela Stegmuller; Victoria B Chou; Hamish R Graham
Journal:  BMJ Glob Health       Date:  2021-12

3.  Cost-effectiveness and sustainability of improved hospital oxygen systems in Nigeria.

Authors:  Hamish R Graham; Ayobami A Bakare; Adejumoke Idowu Ayede; Joseph Eleyinmi; Oyaniyi Olatunde; Oluwabunmi R Bakare; Blessing Edunwale; Eleanor F G Neal; Shamim Qazi; Barbara McPake; David Peel; Amy Z Gray; Trevor Duke; Adegoke G Falade
Journal:  BMJ Glob Health       Date:  2022-08

4.  Technology to improve reliable access to oxygen in Western Uganda: study protocol for a phased implementation trial in neonatal and paediatric wards.

Authors:  Hamish Graham; Bryn Sobott; Sheillah Bagayana; Rami Subhi; Graham Moore; Joseph Mugerwa; David Peake; Eleanor Nakintu; Daniel Murokora; Roger Rassool; Marc Sklar
Journal:  BMJ Open       Date:  2022-06-28       Impact factor: 3.006

5.  Oxygen systems and quality of care for children with pneumonia, malaria and diarrhoea: Analysis of a stepped-wedge trial in Nigeria.

Authors:  Hamish R Graham; Jaclyn Maher; Ayobami A Bakare; Cattram D Nguyen; Adejumoke I Ayede; Oladapo B Oyewole; Amy Gray; Rasa Izadnegahdar; Trevor Duke; Adegoke G Falade
Journal:  PLoS One       Date:  2021-07-08       Impact factor: 3.240

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.