| Literature DB >> 33064630 |
Rabeea Siddique1,2, Qian Bai1,2, Muhammad Adnan Shereen3, Ghulam Nabi4, Guang Han5, Farooq Rashid6, Saeed Ahmed1,2, Aigerim Benzhanova1, Mengzhou Xue1,2, Suliman Khan1,2.
Abstract
A novel coronavirus (2019-nCov) emerged in China, at the end of December 2019 which posed an International Public Health Emergency, and later declared as a global pandemic by the World Health Organization (WHO). The International Committee on Taxonomy of Viruses (ICTV) named it SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2), while the disease was named COVID-19 (Coronavirus Disease- 2019). Many questions related to the exact mode of transmission, animal origins, and antiviral therapeutics are not clear yet. Nevertheless, it is required to urgently launch a new protocol to evaluate the side effects of unapproved vaccines and antiviral therapeutics to accelerate the clinical application of new drugs. In this review, we highlight the most salient characteristics and recent findings of COVID-19 disease, molecular virology, interspecies mechanisms, and health consequences related to this disease.Entities:
Keywords: SARS-CoV-2; covid-19; genome; human health; therapeutic options; vaccine development
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Year: 2020 PMID: 33064630 PMCID: PMC8018497 DOI: 10.1080/21645515.2020.1824497
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN: 2164-5515 Impact factor: 3.452