Susi Araújo Alves1, Emanuela Virginia Cavalcante1, Narjara Tiane Melo1, Ana Corina Lima1, Eduardo Just E Silva2, Geisy Maria de Lima3, Jose Natal Figueiroa4, João Guilherme Alves5. 1. Department of Pediatrics, Faculdade Pernambucana de Saúde (FPS), Recife, Brazil. 2. Department of Radiology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil. 3. Department of Neonatology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil. 4. Department of Biostatistics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil. 5. Department of Pediatrics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Abstract
Background: Fat distribution is associated with chronic diseases and birth weight may influence fat distribution throughout life. Our aim was to compare fat distribution in children born extremely low birth weight (ELBW) and very low birth weight (VLBW). Methods: This retrospective cohort study evaluated children born ELBW and VLBW around the 7th year of life. Fat distribution was assessed by ultrasonography measurements of abdominal subcutaneous and visceral fat thickness. Multiple linear regression analysis was performed. Results: We studied 63 children. Visceral fat thickness but not subcutaneous fat thickness was significantly increased in children born ELBW compared with children born VLBW, respectively, 3.13 (±1.08) versus 1.86 (±0.76) mm. This result remained after adjustment for age, gender, and BMI; adjusted coefficient 0.118, 95% confidence interval 0.009-0.227, p = 0.034. Conclusion: Children born ELBW seem to have increased visceral fat thickness compared with children born VLBW.
Background: Fat distribution is associated with chronic diseases and birth weight may influence fat distribution throughout life. Our aim was to compare fat distribution in children born extremely low birth weight (ELBW) and very low birth weight (VLBW). Methods: This retrospective cohort study evaluated children born ELBW and VLBW around the 7th year of life. Fat distribution was assessed by ultrasonography measurements of abdominal subcutaneous and visceral fat thickness. Multiple linear regression analysis was performed. Results: We studied 63 children. Visceral fat thickness but not subcutaneous fat thickness was significantly increased in children born ELBW compared with children born VLBW, respectively, 3.13 (±1.08) versus 1.86 (±0.76) mm. This result remained after adjustment for age, gender, and BMI; adjusted coefficient 0.118, 95% confidence interval 0.009-0.227, p = 0.034. Conclusion:Children born ELBW seem to have increased visceral fat thickness compared with children born VLBW.
Authors: Juho Kuula; Jesper Lundbom; Antti Hakkarainen; Petteri Hovi; Helena Hauta-Alus; Nina Kaseva; Samuel Sandboge; Johan Björkqvist; Johan Eriksson; Kirsi H Pietiläinen; Nina Lundbom; Eero Kajantie Journal: Sci Rep Date: 2022-06-14 Impact factor: 4.996