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Literature DB >> 3306404

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme.

Abstract

The RAD6 gene of the yeast Saccharomyces cerevisiae is required for a variety of cellular functions including DNA repair. The discovery that the RAD6 gene product can catalyse the covalent attachment of ubiquitin to other proteins suggests that the multiple functions of the RAD6 protein are mediated by its ubiquitin-conjugating activity.

Entities: Gene Species

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Year: 1987 PMID： 3306404 DOI： 10.1038/329131a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

224 in total

1. The 26S proteasome negatively regulates the level of overall genomic nucleotide excision repair.

Authors: L Lommel; L Chen; K Madura; K Sweder
Journal: Nucleic Acids Res Date: 2000-12-15 Impact factor: 16.971

2. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair.

Authors: H D Ulrich; S Jentsch
Journal: EMBO J Date: 2000-07-03 Impact factor: 11.598

Review 3. When repair meets chromatin. First in series on chromatin dynamics.

Authors: Catherine M Green; Geneviève Almouzni
Journal: EMBO Rep Date: 2002-01 Impact factor: 8.807

4. Creation of a pluripotent ubiquitin-conjugating enzyme.

Authors: C Ptak; C Gwozd; J T Huzil; T J Gwozd; G Garen; M J Ellison
Journal: Mol Cell Biol Date: 2001-10 Impact factor: 4.272

Review 5. Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin.

Authors: Helle D Ulrich
Journal: Eukaryot Cell Date: 2002-02

6. A ubiquitin carrier protein from wheat germ is structurally and functionally similar to the yeast DNA repair enzyme encoded by RAD6.

Authors: M L Sullivan; R D Vierstra
Journal: Proc Natl Acad Sci U S A Date: 1989-12 Impact factor: 11.205

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme.

1. The 26S proteasome negatively regulates the level of overall genomic nucleotide excision repair.

2. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair.

Review 3. When repair meets chromatin. First in series on chromatin dynamics.

4. Creation of a pluripotent ubiquitin-conjugating enzyme.

Review 5. Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin.

6. A ubiquitin carrier protein from wheat germ is structurally and functionally similar to the yeast DNA repair enzyme encoded by RAD6.

7. ATPase and ubiquitin-binding proteins of the yeast proteasome.

8. Caffeine-mediated override of checkpoint controls. A requirement for rhp6 (Schizosaccharomyces pombe).

9. Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

10. Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response.