PURPOSE: While the overall impact of chronic rhinosinusitis (CRS) on patients' health is diverse, many affected individuals have a substantially impaired quality of life (QoL). The aim of this study was to evaluate the impact of sex-associated differences specifically in the subgroups of CRS with nasal polyps (CRSwNP) and aspirin-exacerbated respiratory disease (AERD) by assessing QoL parameters in women and men separately. METHODS: In a retrospective single-center study, 59 patients with CRSwNP (39 males and 20 females) and 46 patients with AERD (18 males and 28 females) were included. Patient-reported outcome measures (PROM) evaluating QoL via the Sino-Nasal Outcome Test-20 German Adapted Version (SNOT-20 GAV) as well as the total polyp score (TPS) were analysed. RESULTS: There was no significant difference in TPS (p = 0.5550) and total SNOT-20 GAV scores (p = 0.0726) between male or female patients with CRSwNP or AERD. Furthermore, no significant sex differences were found within disease groups regarding the subcategories of the SNOT-20 GAV items. CONCLUSION: Thus, quality of life is severely impaired in patients suffering from various forms of CRS regardless of their sex.
PURPOSE: While the overall impact of chronic rhinosinusitis (CRS) on patients' health is diverse, many affected individuals have a substantially impaired quality of life (QoL). The aim of this study was to evaluate the impact of sex-associated differences specifically in the subgroups of CRS with nasal polyps (CRSwNP) and aspirin-exacerbated respiratory disease (AERD) by assessing QoL parameters in women and men separately. METHODS: In a retrospective single-center study, 59 patients with CRSwNP (39 males and 20 females) and 46 patients with AERD (18 males and 28 females) were included. Patient-reported outcome measures (PROM) evaluating QoL via the Sino-Nasal Outcome Test-20 German Adapted Version (SNOT-20 GAV) as well as the total polyp score (TPS) were analysed. RESULTS: There was no significant difference in TPS (p = 0.5550) and total SNOT-20 GAV scores (p = 0.0726) between male or female patients with CRSwNP or AERD. Furthermore, no significant sex differences were found within disease groups regarding the subcategories of the SNOT-20 GAV items. CONCLUSION: Thus, quality of life is severely impaired in patients suffering from various forms of CRS regardless of their sex.
Authors: Devyani Lal; Kimberly B Golisch; Zachary A Elwell; Rohit D Divekar; Matthew A Rank; Yu-Hui Chang Journal: Int Forum Allergy Rhinol Date: 2016-04-15 Impact factor: 3.858
Authors: D Hastan; W J Fokkens; C Bachert; R B Newson; J Bislimovska; A Bockelbrink; P J Bousquet; G Brozek; A Bruno; S E Dahlén; B Forsberg; M Gunnbjörnsdóttir; L Kasper; U Krämer; M L Kowalski; B Lange; B Lundbäck; E Salagean; A Todo-Bom; P Tomassen; E Toskala; C M van Drunen; J Bousquet; T Zuberbier; D Jarvis; P Burney Journal: Allergy Date: 2011-05-24 Impact factor: 13.146
Authors: Deborah Bartz; Tanuja Chitnis; Ursula B Kaiser; Janet W Rich-Edwards; Kathryn M Rexrode; Page B Pennell; Jill M Goldstein; Mary Angela O'Neal; Meryl LeBoff; Maya Behn; Ellen W Seely; Hadine Joffe; JoAnn E Manson Journal: JAMA Intern Med Date: 2020-04-01 Impact factor: 21.873