A rare case of a giant anterior mediastinal liposarcoma.

We report a case of a 53-year-old lady who was incidentally diagnosed to have giant anterior mediastinal mass while undergoing preoperative evaluation for another surgery. She came for surgery after 2 years when she became symptomatic. A large 6.7-lb (2800 g) tumor occupying both hemithoraces and engulfing heart was excised in its entirety through a clamshell thoracotomy under cardiopulmonary bypass standby. Histopathology revealed the final diagnosis as well as differentiated liposarcoma. She is now able to walk 2 km without any symptoms at the end of a 24-month follow-up. © Indian Association of Cardiovascular-Thoracic Surgeons 2019.