Literature DB >> 33060964

'CLAS' score: an objective tool to standardize and predict mitral valve repairability.

Amber Malhotra1, Sumbul Siddiqui1, Vivek Wadhawa1, Himani Pandya2, Kartik Patel1, Komal Shah2, Hemang Gandhi3, Pankaj Garg1, Sudhir Adalti1, Kamal Sharma4.   

Abstract

PURPOSE: Carpentier's classification has been used to classify both stenotic and regurgitant lesions. However, given the extreme variability of lesions, a universal nomenclature suggestive of the complexity and the prognosis of the repair procedure for the entire spectrum of the mitral valve disease still remains elusive. We present the predictors of mitral valve repairability with the help of a four-level-based 'CLAS' scoring system.
METHODS: A total of 394 patients undergoing mitral valve procedure were prospectively studied. The valvular apparatus was divided into four sub-units, namely Commissures (C), Leaflet (L), Annulus (A), and Subvalvular apparatus (S), and the components were scored individually and the summation scores were calculated. Based on our results, three CLAS groups were formulated.
RESULTS: A total of 376 (n = 394) patients underwent successful MVRep (95.43%; on-table failure in 18 patients). A total of 276 were rheumatic, 51 degenerative, 28 congenital, and 16 had infective endocarditis. Thirty-day mortality was 14 (3.72%) while delayed re-intervention rate was 8 (2.12%). The mean follow-up period was 30 months. One hundred percent patients with a CLAS score ≤ 8 had a successful repair as compared to 93.33 and 69.69%, respectively, for patients with scores between 9 and 12 and > 12, respectively. The cardio pulmonary bypass time, aortic-cross-clamp time, and ICU stay also showed a significant correlation with the patient's 'CLAS' groups.
CONCLUSION: The CLAS score is highly predictive of a successful repair. We thus propose that, in the patients with a score of ≤ 8, repair should always be attempted irrespective of the pathology. The patients expected to be scored > 8 should be referred to a repair reference center. © Indian Association of Cardiovascular-Thoracic Surgeons 2018.

Entities:  

Keywords:  Mitral regurgitation; Mitral valve repair; Rheumatic heart disease

Year:  2018        PMID: 33060964      PMCID: PMC7525520          DOI: 10.1007/s12055-018-0721-4

Source DB:  PubMed          Journal:  Indian J Thorac Cardiovasc Surg        ISSN: 0970-9134


  16 in total

1.  Results of mitral valve repair in rheumatic mitral regurgitation.

Authors:  Arkalgud Sampath Kumar; Sachin Talwar; Anita Saxena; Rajvir Singh; Devagourou Velayoudam
Journal:  Interact Cardiovasc Thorac Surg       Date:  2006-04-03

Review 2.  Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents.

Authors:  Martina Rothenbühler; Crochan J O'Sullivan; Stefan Stortecky; Giulio G Stefanini; Ernest Spitzer; Janne Estill; Nikesh R Shrestha; Olivia Keiser; Peter Jüni; Thomas Pilgrim
Journal:  Lancet Glob Health       Date:  2014-12       Impact factor: 26.763

3.  Long-term (29 years) results of reconstructive surgery in rheumatic mitral valve insufficiency.

Authors:  S Chauvaud; J F Fuzellier; A Berrebi; A Deloche; J N Fabiani; A Carpentier
Journal:  Circulation       Date:  2001-09-18       Impact factor: 29.690

4.  Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience.

Authors:  Tirone E David; Susan Armstrong; Joan Ivanov
Journal:  J Thorac Cardiovasc Surg       Date:  2012-06-17       Impact factor: 5.209

5.  Mitral valve repair in a predominantly rheumatic population. Long-term results.

Authors:  S K Choudhary; S Talwar; B Dubey; A Chopra; A Saxena; A S Kumar
Journal:  Tex Heart Inst J       Date:  2001

6.  Large annuloplasty rings facilitate mitral valve repair in Barlow's disease.

Authors:  David H Adams; Ani C Anyanwu; Parwis B Rahmanian; Vivian Abascal; Sacha P Salzberg; Farzan Filsoufi
Journal:  Ann Thorac Surg       Date:  2006-12       Impact factor: 4.330

7.  A near 100% repair rate for mitral valve prolapse is achievable in a reference center: implications for future guidelines.

Authors:  Javier G Castillo; Anelechi C Anyanwu; Valentin Fuster; David H Adams
Journal:  J Thorac Cardiovasc Surg       Date:  2012-06-12       Impact factor: 5.209

8.  Artificial chordae.

Authors:  Tirone E David
Journal:  Semin Thorac Cardiovasc Surg       Date:  2004

9.  Anterior leaflet augmentation with autologous pericardium for mitral repair in rheumatic valve insufficiency.

Authors:  Christophe Acar; José Saez de Ibarra; Emmanuel Lansac
Journal:  J Heart Valve Dis       Date:  2004-09

10.  A simple method to obtain the correct length of the artificial chordae in complex chordal replacement.

Authors:  Antonio M Calafiore; Salvatore Scandura; Angela L Iacò; Marco Contini; Michele Di Mauro; Antonio Bivona; Guido Giordano; Paolo Bosco
Journal:  J Card Surg       Date:  2008 May-Jun       Impact factor: 1.620

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  2 in total

1.  Rheumatic mitral valve repair in the developing world: 'a very different ball game'.

Authors:  Kartik Patel; Amber Malhotra
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2021-09-28

2.  Repairing the rheumatic mitral valve in the young: The horizon revisited.

Authors:  Chandrasekaran Ananthanarayanan; Amber Malhotra; Sumbul Siddiqui; Pratik Shah; Himani Pandya; Pranav Sharma; Anand Shukla; Rajesh Thosani
Journal:  JTCVS Open       Date:  2020-03-06
  2 in total

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