Literature DB >> 33057887

Effect of St. John's wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial.

Volkan Kaplan1, Guzin Neda Hasanoglu Erbasar2, Levent Cigerim3, Hilal Altay Turgut2, Abdullah Cerit4.   

Abstract

OBJECTIVES: This multicenter study aimed to evaluate the effects of St. John's wort oil and virgin olive oil on the postoperative complications and compare this with chlorhexidine gluconate plus benzydamine hydrochloride mouthwash after the removal of impacted third molar.
METHODS: A total of 90 patients in need of impacted third molar surgery were included in this study. All included patients were randomly divided into 3 groups. The patients in group 1 received St. John's wort oil; the patients in group 2 received virgin olive oil, and those in group 3 received mouthwash containing chlorhexidine gluconate plus benzydamine hydrochloride. The self-reported pain and difficulty during jaw function, trismus, facial swelling, number of analgesics used during first postoperative week, and postoperative periodontal condition including plaque accumulation, bleeding on probing, and periodontal pocket depth were compared between the groups.
RESULTS: No significant differences were found regarding the study variables.
CONCLUSIONS: The data of the present study supports that the use of essential oils provides efficient alternative to the gold standard chlorhexidine gluconate mouthwash in reducing postoperative complications and improving healing process without adverse effects after surgical removal of impacted third molars. CLINICAL RELEVANCE: The use of essential oils showed similar results as the chlorhexidine gluconate mouthwash regarding swelling, mouth opening, pain, need for rescue medication, infectious complications (i.e., alveolar osteitis), and periodontal healing. Therefore, essential oils can be an alternative to routine mouthwashes to ensure oral hygiene after impacted third molar surgery.

Entities:  

Keywords:  Chlorhexidine; Impacted tooth; Olive oil; Postoperative complications; St. John’s wort

Mesh:

Substances:

Year:  2020        PMID: 33057887     DOI: 10.1007/s00784-020-03639-0

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  37 in total

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Authors:  Srinivas M Susarla; Bart F Blaeser; Daniel Magalnick
Journal:  Oral Maxillofac Surg Clin North Am       Date:  2003-05       Impact factor: 2.802

2.  Randomized, double-blind study of effectiveness of intra-alveolar application of chlorhexidine gel in reducing incidence of alveolar osteitis and bleeding complications in mandibular third molar surgery in patients with bleeding disorders.

Authors:  Daniel Torres-Lagares; Jose Luis Gutierrez-Perez; Pilar Hita-Iglesias; Natale Magallanes-Abad; Rafael Flores-Ruiz; Marta Basallote-Garcia; Maribel Gonzalez-Martin
Journal:  J Oral Maxillofac Surg       Date:  2010-03-25       Impact factor: 1.895

3.  Cytopathologic effects of chlorhexidine on human cells.

Authors:  P Goldschmidt; R Cogen; S Taubman
Journal:  J Periodontol       Date:  1977-04       Impact factor: 6.993

4.  The effect of sodium hypochlorite and chlorhexidine on cultured human periodontal ligament cells.

Authors:  Y C Chang; F M Huang; K W Tai; M Y Chou
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2001-10

5.  Effect of chlorhexidine digluconate on different cell types: a molecular and ultrastructural investigation.

Authors:  M Giannelli; F Chellini; M Margheri; P Tonelli; A Tani
Journal:  Toxicol In Vitro       Date:  2007-11-05       Impact factor: 3.500

6.  Pharmacokinetics of benzydamine after intravenous, oral, and topical doses to human subjects.

Authors:  G A Baldock; R R Brodie; L F Chasseaud; T Taylor; L M Walmsley; B Catanese
Journal:  Biopharm Drug Dispos       Date:  1991-10       Impact factor: 1.627

7.  Cytotoxicity of mouthrinses on epithelial cells by micronucleus test.

Authors:  Ebru Olgun Erdemir; Abdulkadir Sengün; Mustafa Ulker
Journal:  Eur J Dent       Date:  2007-04

8.  Genotoxic assessment of chlorhexidine mouthwash on exfoliated buccal epithelial cells in chronic gingivitis patients.

Authors:  Saif Khan; Asad Ullah Khan; Sadaf Hasan
Journal:  J Indian Soc Periodontol       Date:  2016 Nov-Dec

9.  Evaluation of the analgesic efficacies of Dexketoprofen Trometamol and Dexketoprofen Trometamol + Thiocolchicoside combinations in the impacted third molar surgery: Randomised clinical trial.

Authors:  L Cigerim; V Kaplan
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2019-01-01

10.  Evaluation of postoperative complications according to treatment of third molars in mandibular angle fracture.

Authors:  Hye-Youn Lim; Tae-Young Jung; Sang-Jun Park
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2017-02-20
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3.  Biocompatibility and Effectiveness of a Novel, Organic Olive Oil-Based Denture Adhesive: A Multicenter Randomized and Placebo-Controlled Clinical Trial.

Authors:  Luís Azevedo; André Correia; Carlos F Almeida; Pedro Molinero-Mourelle; Maria Correia; Jaime Del Río Highsmith
Journal:  Int J Environ Res Public Health       Date:  2021-03-25       Impact factor: 3.390

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