Literature DB >> 33055482

A Case of Smoke Bomb-induced Acute Lung Injury.

Hideki Sakakibara1, Kei Yamasaki1, Shiro Ono2, Kazuhiro Yatera1.   

Abstract

Entities:  

Keywords:  acute respiratory failure; smoke bomb; zinc chloride

Year:  2020        PMID: 33055482      PMCID: PMC8024971          DOI: 10.2169/internalmedicine.5708-20

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


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A 37-year-old Japanese man developed dyspnea, nonproductive cough, and a fever soon after inhaling smoke from a zinc chloride-based smoke bomb in a closed room during a fire-fighting drill. Three days later, he visited our hospital with worsening dyspnea, and his oxyhemoglobin saturation was 89% on room air. Chest computed tomography (CT) revealed bilateral patchy ground glass attenuations (Picture 1A). The bronchoalveolar lavage fluid obtained from S1+2, which had a recovery rate of 60% (90/150 mL), was slightly bloody. The cell count was normal (0.79×105/mL), including macrophages (74%) (including hemosiderin-laden macrophages), lymphocytes (13%), neutrophils (7%), and eosinophils (6%) (Picture 1B). Bacterial culture was negative. He was diagnosed with acute lung injury with alveolar hemorrhaging. His clinical condition and CT findings completely recovered soon after the administration of methylprednisolone (125 mg/day for 3 days) and subsequent oral prednisolone (30 mg/day for 5 days) (Picture 2). Zinc chloride-based smoke bombs are used in fire and military drills, but a few cases of acute respiratory failure during a fire-fighting drill have been reported (1, 2). Physicians should keep in mind that acute respiratory failure can occur even 24 hours after toxic gas inhalation.
Picture 1.
Picture 2.

The authors state that they have no Conflict of Interest (COI).
  2 in total

Review 1.  The toxicology of zinc chloride smoke producing bombs and screens.

Authors:  Ayman El Idrissi; Lisanne van Berkel; Nadia E Bonekamp; Diana J Z Dalemans; Marcel A G van der Heyden
Journal:  Clin Toxicol (Phila)       Date:  2017-01-11       Impact factor: 4.467

2.  A fatal case following exposure to zinc chloride and hexachloroethane from a smoke bomb in a fire simulation at a school.

Authors:  Fernando Gil; Antonio Pla; Antonio F Hernández; Juan M Mercado; Fernando Méndez
Journal:  Clin Toxicol (Phila)       Date:  2008-07       Impact factor: 4.467

  2 in total

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