Literature DB >> 33054391

Macrophage Biology in Cardiovascular Diseases.

Mitri K Khoury1, Huan Yang1, Bo Liu1.   

Abstract

Macrophages have a key functional role in the pathogenesis of various cardiovascular diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the vessel wall leads to sustained local inflammatory responses characterized by secretion of chemokines, cytokines, and matrix protein degrading enzymes. Here, we summarize some recent findings on macrophage contribution to cardiovascular disease. We focus on the origin, survival/death, and phenotypic switching of macrophages within vessel walls.

Entities:  

Keywords:  cardiovascular diseases; cytokines; elastin; hypercholesterolemia; monocytes

Mesh：

Substances：

Year:  2020        PMID： 33054391      PMCID： PMC8046835          DOI： 10.1161/ATVBAHA.120.313584

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


  55 in total

1.  Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.

Authors:  Vladimir R Babaev; Lei Ding; Youmin Zhang; James M May; Stephen A Ramsey; Kasey C Vickers; MacRae F Linton
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-02       Impact factor: 8.311

2.  Chemokines as Therapeutic Targets in Cardiovascular Disease.

Authors:  Heidi Noels; Christian Weber; Rory R Koenen
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-04       Impact factor: 8.311

Review 3.  Updates of Recent Aortic Aneurysm Research.

Authors:  Frank M Davis; Alan Daugherty; Hong S Lu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-03       Impact factor: 8.311

4.  Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis.

Authors:  Sima Allahverdian; Ali Cyrus Chehroudi; Bruce M McManus; Thomas Abraham; Gordon A Francis
Journal:  Circulation       Date:  2014-01-30       Impact factor: 29.690

5.  Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.

Authors:  Minako Ishibashi; Kensuke Egashira; Qingwei Zhao; Ken-ichi Hiasa; Kisho Ohtani; Yoshiko Ihara; Israel F Charo; Shinobu Kura; Teruhisa Tsuzuki; Akira Takeshita; Kenji Sunagawa
Journal:  Arterioscler Thromb Vasc Biol       Date:  2004-08-26       Impact factor: 8.311

6.  Blocking TNF-alpha attenuates aneurysm formation in a murine model.

Authors:  Wanfen Xiong; Jason MacTaggart; Rebecca Knispel; Jennifer Worth; Yuri Persidsky; B Timothy Baxter
Journal:  J Immunol       Date:  2009-07-20       Impact factor: 5.422

7.  Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture.

Authors:  Wei Luo; Yidan Wang; Lin Zhang; Pingping Ren; Chen Zhang; Yanming Li; Alon R Azares; Michelle Zhang; Jiao Guo; Ketan B Ghaghada; Zbigniew A Starosolski; Kimal Rajapakshe; Cristian Coarfa; Yumei Li; Rui Chen; Keigi Fujiwara; Jun-Ichi Abe; Joseph S Coselli; Dianna M Milewicz; Scott A LeMaire; Ying H Shen
Journal:  Circulation       Date:  2019-12-30       Impact factor: 29.690

8.  Single-cell immune landscape of human atherosclerotic plaques.

Authors:  Dawn M Fernandez; Adeeb H Rahman; Nicolas F Fernandez; Aleksey Chudnovskiy; El-Ad David Amir; Letizia Amadori; Nayaab S Khan; Christine K Wong; Roza Shamailova; Christopher A Hill; Zichen Wang; Romain Remark; Jennifer R Li; Christian Pina; Christopher Faries; Ahmed J Awad; Noah Moss; Johan L M Bjorkegren; Seunghee Kim-Schulze; Sacha Gnjatic; Avi Ma'ayan; J Mocco; Peter Faries; Miriam Merad; Chiara Giannarelli
Journal:  Nat Med       Date:  2019-10-07       Impact factor: 53.440

9.  Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models.

Authors:  Ting Zhou; Qiwei Wang; Noel Phan; Jun Ren; Huan Yang; Conner C Feldman; John B Feltenberger; Zhengqing Ye; Scott A Wildman; Weiping Tang; Bo Liu
Journal:  Cell Death Dis       Date:  2019-03-06       Impact factor: 8.469

10.  Local proliferation dominates lesional macrophage accumulation in atherosclerosis.

Authors:  Clinton S Robbins; Ingo Hilgendorf; Georg F Weber; Igor Theurl; Yoshiko Iwamoto; Jose-Luiz Figueiredo; Rostic Gorbatov; Galina K Sukhova; Louisa M S Gerhardt; David Smyth; Caleb C J Zavitz; Eric A Shikatani; Michael Parsons; Nico van Rooijen; Herbert Y Lin; Mansoor Husain; Peter Libby; Matthias Nahrendorf; Ralph Weissleder; Filip K Swirski
Journal:  Nat Med       Date:  2013-08-11       Impact factor: 53.440
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  8 in total

1.  Autophagy enhanced by curcumin ameliorates inflammation in atherogenesis via the TFEB-P300-BRD4 axis.

Authors:  Xuesong Li; Ruigong Zhu; Hong Jiang; Quanwen Yin; Jiaming Gu; Jiajing Chen; Xian Ji; Xuan Wu; Haiping Fu; Hui Wang; Xin Tang; Yuanqing Gao; Bingjian Wang; Yong Ji; Hongshan Chen
Journal:  Acta Pharm Sin B       Date:  2021-12-29       Impact factor: 14.903

2.  Exosomal MALAT1 Derived from High Glucose-Treated Macrophages Up-Regulates Resistin Expression via miR-150-5p Downregulation.

Authors:  Kou-Gi Shyu; Bao-Wei Wang; Wei-Jen Fang; Chun-Ming Pan; Chiu-Mei Lin
Journal:  Int J Mol Sci       Date:  2022-01-20       Impact factor: 5.923

Review 3.  Inflammatory Cells in Atherosclerosis.

Authors:  Marcelle Mehu; Chandrakala Aluganti Narasimhulu; Dinender K Singla
Journal:  Antioxidants (Basel)       Date:  2022-01-26

4.  Single-Cell Sequencing of Immune Cells in Human Aortic Dissection Tissue Provides Insights Into Immune Cell Heterogeneity.

Authors:  Yifan Liu; Lingwei Zou; Hanfei Tang; Jie Li; Hao Liu; Xiaolang Jiang; Baohong Jiang; Zhihui Dong; Weiguo Fu
Journal:  Front Cardiovasc Med       Date:  2022-03-31

Review 5.  Inflammation and atherosclerosis: signaling pathways and therapeutic intervention.

Authors:  Peng Kong; Zi-Yang Cui; Xiao-Fu Huang; Dan-Dan Zhang; Rui-Juan Guo; Mei Han
Journal:  Signal Transduct Target Ther       Date:  2022-04-22

Review 6.  Role of ABCA1 in Cardiovascular Disease.

Authors:  Jing Wang; Qianqian Xiao; Luyun Wang; Yan Wang; Daowen Wang; Hu Ding
Journal:  J Pers Med       Date:  2022-06-20

7.  Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase.

Authors:  Anchit Bhagat; Pradeep Shrestha; Prince Jeyabal; Zhanglong Peng; Stephanie S Watowich; Eugenie S Kleinerman
Journal:  Front Oncol       Date:  2022-08-10       Impact factor: 5.738

Review 8.  Recent Advances of Cell Membrane Coated Nanoparticles in Treating Cardiovascular Disorders.

Authors:  Chaojie Zhu; Junkai Ma; Zhiheng Ji; Jie Shen; Qiwen Wang
Journal:  Molecules       Date:  2021-06-05       Impact factor: 4.411
  8 in total

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