Literature DB >> 33047143

Radiographic features of COVID-19 based on an initial cohort of 96 patients in Singapore.

Hau Wei Wei Khoo1, Terrence Chi Hong Hui1, Salahudeen Mohamed Haja Mohideen2, Yeong Shyan Lee1, Charlene Jin Yee Liew3,4, Shawn Shi Xian Kok5, Barnaby Edward Young6,7, Sean Wei Xiang Ong6,7, Shirin Kalimuddin4,8, Seow Yen Tan9, Jiashen Loh10, Lai Peng Chan2,11, Angeline Choo Choo Poh3, Steven Bak Siew Wong5, Yee-Sin Leo6,7,11,12,13, David Chien Lye6,7,11,13, Gregory Jon Leng Kaw1, Cher Heng Tan1,13.   

Abstract

INTRODUCTION: Chest radiographs (CXRs) are widely used for the screening and management of COVID-19. This article describes the radiographic features of COVID-19 based on an initial national cohort of patients.
METHODS: This is a retrospective review of swab-positive patients with COVID-19 who were admitted to four different hospitals in Singapore between 22 January and 9 March 2020. Initial and follow-up CXRs were reviewed by three experienced radiologists to identify the predominant pattern and distribution of lung parenchymal abnormalities.
RESULTS: In total, 347 CXRs of 96 patients were reviewed. Initial CXRs were abnormal in 41 (42.7%) out of 96 patients. The mean time from onset of symptoms to CXR abnormality was 5.3 ± 4.7 days. The predominant pattern of lung abnormality was ground-glass opacity on initial CXRs (51.2%) and consolidation on follow-up CXRs (51.0%). Multifocal bilateral abnormalities in mixed central and peripheral distribution were observed in 63.4% and 59.2% of abnormal initial and follow-up CXRs, respectively. The lower zones were involved in 90.2% of initial CXRs and 93.9% of follow-up CXRs.
CONCLUSION: In a cohort of swab-positive patients, including those identified from contact tracing, we found a lower incidence of CXR abnormalities than was previously reported. The most common pattern was ground-glass opacity or consolidation, but mixed central and peripheral involvement was more common than peripheral involvement alone. Copyright: © Singapore Medical Association.

Entities:  

Keywords:  SARS-CoV-2; chest radiographs; coronavirus disease 2019

Mesh:

Year:  2020        PMID: 33047143      PMCID: PMC9251244          DOI: 10.11622/smedj.2020142

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   3.331


  29 in total

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