Literature DB >> 33043888

Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India.

Pavan Kalamdani1, Thaslima Kalathingal1, Swati Manerkar2, Jayashree Mondkar1.   

Abstract

OBJECTIVE: To describe the clinical and laboratory profile of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected neonates.
METHODS: This is a review of hospital records, conducted in a tertiary care public hospital. Medical records of neonates born from 1 April, 2020 to 31 May, 2020 were reviewed. Women admitted in labor were screened for SARS-CoV-2 infection based on the guidelines issued by Indian Council for Medical Research. Neonates were tested for SARS-CoV-2 infection once mother tested positive, which was after day 2 of life. Demographic, clinical features, laboratory tests and chest radiographs of SARS-CoV-2 infected neonates were reviewed and neonates were telephonically followed up till the age of 2 months.
RESULTS: Out of 1229 mothers, 185 tested positive (15.05%); 12 neonates (6.48%) tested positive for SARS-CoV-2 infection. All neonates were exclusively breastfed. Symptoms, if any, were mild and self-limiting. Serum lactate dehydrogenase and liver enzymes were elevated. All neonates were healthy and thriving well on follow-up.
CONCLUSION: SARS-CoV-2 infected neonates are mostly asymptomatic and thrive well on exclusive breastfeeding.

Entities:  

Mesh:

Year:  2020        PMID: 33043888      PMCID: PMC7781822     

Source DB:  PubMed          Journal:  Indian Pediatr        ISSN: 0019-6061            Impact factor:   3.839


  10 in total

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2.  Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study.

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Review 3.  The clinical course of SARS-CoV-2 positive neonates.

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Review 4.  Laboratory abnormalities in children with mild and severe coronavirus disease 2019 (COVID-19): A pooled analysis and review.

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Journal:  Clin Biochem       Date:  2020-05-27       Impact factor: 3.281

Review 5.  Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis.

Authors:  Brandon Michael Henry; Gaurav Aggarwal; Johnny Wong; Stefanie Benoit; Jens Vikse; Mario Plebani; Giuseppe Lippi
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6.  Perinatal-Neonatal Management of COVID-19 Infection - Guidelines of the Federation of Obstetric and Gynaecological Societies of India (FOGSI), National Neonatology Forum of India (NNF), and Indian Academy of Pediatrics (IAP).

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Journal:  Indian Pediatr       Date:  2020-04-01       Impact factor: 1.411

7.  Intrauterine vertical transmission of SARS-CoV-2: what we know so far.

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8.  Infants Born to Mothers With a New Coronavirus (COVID-19).

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9.  Clinical Features and Outcome of SARS-CoV-2 Infection in Neonates: A Systematic Review.

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10.  Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis.

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  10 in total
  10 in total

Review 1.  Clinical Outcome of Neonates Born to SARS-CoV-2 Positive Mothers in India: A Systematic Review and Meta-Analysis.

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2.  COVID-19 guidelines for pregnant women and new mothers: A systematic evidence review.

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3.  A single-center observational study on clinical features and outcomes of 21 SARS-CoV-2-infected neonates from India.

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Review 4.  A Comprehensive Analysis of Maternal and Newborn Disease and Related Control for COVID-19.

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5.  Small and sick newborn care during the COVID-19 pandemic: global survey and thematic analysis of healthcare providers' voices and experiences.

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Journal:  BMJ Glob Health       Date:  2021-03

6.  Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis.

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Review 7.  Breastfeeding during the COVID-19 pandemic: what do we know so far?

Authors:  Taison Regis Penariol Natarelli; Heloisa Gasparini Marigheti Brassarola; Luciana Mara Monti Fonseca
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8.  Clinical, Laboratory, and Imaging Findings of Pregnant Women with Possible Vertical Transmission of SARS-CoV-2-Case Series.

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9.  Clinical characteristics & outcome of SARS-CoV-2 infected neonates presenting to paediatric emergency.

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Journal:  Indian J Med Res       Date:  2022-01       Impact factor: 5.274

10.  A novel approach to minimize the false negative COVID-19 diagnosis by inclusion of specific cell markers and multiple sample collection.

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  10 in total

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