Literature DB >> 3304381

Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation?

P Rafferty, P M Tweeddale, R J Ferguson, B A Biggs, I W Grant.   

Abstract

Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH). There was no significant difference in the degree of bronchoconstriction produced by IH after treatment with ketotifen or placebo.

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Year:  1987        PMID： 3304381      PMCID： PMC1386287          DOI： 10.1111/j.1365-2125.1987.tb03143.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  15 in total

Review 1.  Exercise-induced asthma: Observations on the initiating stimulus.

Authors:  E R McFadden; R H Ingram
Journal:  N Engl J Med       Date:  1979-10-04       Impact factor: 91.245

2.  Hyperpnea and heat flux: initial reaction sequence in exercise-induced asthma.

Authors:  E C Deal; E R McFadden; R H Ingram; J J Jaeger
Journal:  J Appl Physiol Respir Environ Exerc Physiol       Date:  1979-03

3.  The ventilatory capacity of patients with chronic airways obstruction.

Authors:  T J Clark; S Freedman; E J Campbell; R R Winn
Journal:  Clin Sci       Date:  1969-04       Impact factor: 6.124

Review 4.  Controversies in the pathogenesis of exercise-induced asthma.

Authors:  S Godfrey
Journal:  Eur J Respir Dis       Date:  1986-02

5.  A comparison of the effects of ketotifen and clemastine on cutaneous and airway reactivity to histamine and allergen in atopic asthmatic subjects.

Authors:  S Esau; J del Carpio; J G Martin
Journal:  J Allergy Clin Immunol       Date:  1984-09       Impact factor: 10.793

6.  Hyperventilation or exercise to induce asthma?

Authors:  P M Tweeddale; D J Godden; I W Grant
Journal:  Thorax       Date:  1981-08       Impact factor: 9.139

7.  Ketotifen in atopic asthma and exercise-induced asthma.

Authors:  I S Petheram; J Moxham; C W Bierman; M McAllen; S G Spiro
Journal:  Thorax       Date:  1981-04       Impact factor: 9.139

8.  Antigen bronchial challenge and efficacy after 4 weeks of treatment with ketotifen and disodium cromoglycate.

Authors:  F M Palmen
Journal:  Respiration       Date:  1983       Impact factor: 3.580

9.  Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys.

Authors:  G Lilja; V Graff-Lonnevig; S Bevegård
Journal:  Allergy       Date:  1983-01       Impact factor: 13.146

10.  A comparison of ketotifen with clemastine, ipratropium bromide and sodium cromoglycate in exercise-induced asthma.

Authors:  A J Dorward; K R Patel
Journal:  Clin Allergy       Date:  1982-07
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