Yichao Wang1, Shengliang Zhou2, Xueting Liu3, Shu Rui1, Zhihui Li1, Jingqiang Zhu1, Tao Wei1. 1. Department of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, China. 2. West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China. 3. Department of Evidence-Based Medicine and Clinical Epidemiology, West China Hospital, Sichuan University, Chengdu, China.
Abstract
BACKGROUND: To conduct a meta-analysis to compare the safety and efficacy of transoral endoscopic thyroidectomy vestibular approach (TOETVA) with conventional open thyroidectomy (COT). METHODS: MEDLINE, EMBASE, Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials in the Cochrane Library from January 2007 to March 2020 were searched to identify studies comparing TOETVA and COT. RESULTS: Six eligible nonrandomized studies involving 1151 patients were included. Meta-analysis results revealed that TOETVA group had a significantly longer operative time (weighted mean difference [WMD], 66.09; 95% confidence interval [CI], 35.22-96.96; P < .0001) and larger amount of drainage (WMD, 98; 95% CI, 20.14-175.86; P = .01). There were no significant differences in terms of postoperative outcomes. CONCLUSION: TOETVA appears to be as feasible and safe as the COT for the treatment of patients with benign thyroid nodules and selected differential thyroid carcinomas.
BACKGROUND: To conduct a meta-analysis to compare the safety and efficacy of transoral endoscopic thyroidectomy vestibular approach (TOETVA) with conventional open thyroidectomy (COT). METHODS: MEDLINE, EMBASE, Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials in the Cochrane Library from January 2007 to March 2020 were searched to identify studies comparing TOETVA and COT. RESULTS: Six eligible nonrandomized studies involving 1151 patients were included. Meta-analysis results revealed that TOETVA group had a significantly longer operative time (weighted mean difference [WMD], 66.09; 95% confidence interval [CI], 35.22-96.96; P < .0001) and larger amount of drainage (WMD, 98; 95% CI, 20.14-175.86; P = .01). There were no significant differences in terms of postoperative outcomes. CONCLUSION:TOETVA appears to be as feasible and safe as the COT for the treatment of patients with benign thyroid nodules and selected differential thyroid carcinomas.
Authors: Barbara Martino; Letizia Nitro; Loredana De Pasquale; Paolo Lozza; Alberto Maccari; Luca Castellani; Matilde Piazzoni; Matteo Cardellicchio; Antonio Mario Bulfamante; Carlotta Pipolo; Giovanni Felisati; Alberto Maria Saibene Journal: Int J Med Robot Date: 2022-06-05 Impact factor: 2.483