Literature DB >> 3304285

Partial structure of an insulin-sensitive glycophospholipid.

J M Mato, K L Kelly, A Abler, L Jarett, B E Corkey, J A Cashel, D Zopf.   

Abstract

The structure of a glycophospholipid, which has been involved in insulin action, has been investigated using H35 cells and rat liver membranes. The present evidence indicates that this molecule contains a phosphatidyl-chiro-inositol moiety, glycosidically linked to a non-N-acetylated glucosamine. In addition, the polar head group of the lipid contains galactose, probably four residues, and a total number of three phosphates.

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Year:  1987        PMID： 3304285     DOI： 10.1016/0006-291x(87)90595-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  15 in total

1.  Inositolphosphoglycans are possible mediators of the glucagon-like peptide 1 (7-36)amide action in the liver.

Authors:  M A Trapote; F Clemente; C Galera; M Morales; A I Alcántara; M I López-Delgado; M L Villanueva-Peñacarrillo; I Valverde
Journal:  J Endocrinol Invest       Date:  1996-02       Impact factor: 4.256

2.  Evidence of two isomers of phosphatidylinositol in plant tissue.

Authors:  P P Murthy; G Pliska-Matyshak; L M Keranen; P Lam; H H Mueller; N Bhuvarahamurthy
Journal:  Plant Physiol       Date:  1992-04       Impact factor: 8.340

Review 3.  D-chiro-inositol glycans in insulin signaling and insulin resistance.

Authors:  Joseph Larner; David L Brautigan; Michael O Thorner
Journal:  Mol Med       Date:  2010-08-27       Impact factor: 6.354

4.  Transport in isolated rat hepatocytes of the phospho-oligosaccharide that mimics insulin action. Effects of adrenalectomy and glucocorticoid treatment.

Authors:  J F Alvarez; J A Sánchez-Arias; A Guadaño; F Estévez; I Varela; J E Felíu; J M Mato
Journal:  Biochem J       Date:  1991-03-01       Impact factor: 3.857

5.  Isolation of insulin-sensitive phosphatidylinositol-glycan from rat adipocytes. Its impaired breakdown in the streptozotocin-diabetic rat.

Authors:  S L Macaulay; R G Larkins
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

Review 6.  The role of glycosyl-phosphoinositides in hormone action.

Authors:  A R Saltiel
Journal:  J Bioenerg Biomembr       Date:  1991-02       Impact factor: 2.945

7.  The effect of amino acids, monoamines and polyamines on pyruvate dehydrogenase activity in mitochondria from rat adipocytes.

Authors:  F L Kiechle; H Malinski; D M Dandurand; J B McGill
Journal:  Mol Cell Biochem       Date:  1990-03-27       Impact factor: 3.396

8.  D-chiro-inositol metabolism in diabetes mellitus.

Authors:  R E Ostlund; J B McGill; I Herskowitz; D M Kipnis; J V Santiago; W R Sherman
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

9.  A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol.

Authors:  M A Avila; R Clemente; I Varela-Nieto
Journal:  Biochem J       Date:  1992-03-15       Impact factor: 3.857

10.  Convergence and divergence of the signaling pathways for insulin and phosphoinositolglycans.

Authors:  G Müller; S Wied; C Piossek; A Bauer; J Bauer; W Frick
Journal:  Mol Med       Date:  1998-05       Impact factor: 6.354
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