Literature DB >> 3304060

Interaction of ascorbate and alpha-tocopherol.

E Niki.   

Abstract

Vitamins C and E function as water-soluble and lipid-soluble chain-breaking antioxidants, respectively, and protect lipids, proteins, and membranes from oxidative damage. Vitamin C scavenges oxygen radicals in the aqueous phase, whereas vitamin E scavenges oxygen radicals within the membranes. Vitamin C regenerates vitamin E by reducing vitamin E radicals formed when vitamin E scavenges the oxygen radicals. This interaction between vitamin C and vitamin E radicals can take place not only in homogeneous solutions but also in liposomal membrane systems where vitamins C and E reside separately outside and within the membranes respectively, and vitamin C can act as a synergist.

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Year:  1987        PMID: 3304060     DOI: 10.1111/j.1749-6632.1987.tb23761.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  62 in total

Review 1.  Antioxidant supplementation during exercise training: beneficial or detrimental?

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2.  Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma.

Authors:  Colleen G Le Prell; Larry F Hughes; Josef M Miller
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3.  COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials.

Authors:  Kathryn T Hall; Julie E Buring; Kenneth J Mukamal; M Vinayaga Moorthy; Peter M Wayne; Ted J Kaptchuk; Elisabeth M Battinelli; Paul M Ridker; Howard D Sesso; Stephanie J Weinstein; Demetrius Albanes; Nancy R Cook; Daniel I Chasman
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Review 4.  The chemistry and antioxidant properties of tocopherols and tocotrienols.

Authors:  A Kamal-Eldin; L A Appelqvist
Journal:  Lipids       Date:  1996-07       Impact factor: 1.880

Review 5.  Vitamin C and gastric cancer: supplements for some or fruit for all?

Authors:  P O'Toole; M Lombard
Journal:  Gut       Date:  1996-09       Impact factor: 23.059

Review 6.  Interaction of alcohol with other drugs and nutrients. Implication for the therapy of alcoholic liver disease.

Authors:  C S Lieber
Journal:  Drugs       Date:  1990       Impact factor: 9.546

7.  Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial.

Authors:  Howard D Sesso; Julie E Buring; William G Christen; Tobias Kurth; Charlene Belanger; Jean MacFadyen; Vadim Bubes; JoAnn E Manson; Robert J Glynn; J Michael Gaziano
Journal:  JAMA       Date:  2008-11-09       Impact factor: 56.272

Review 8.  Does antioxidant vitamin supplementation protect against muscle damage?

Authors:  Cian McGinley; Amir Shafat; Alan E Donnelly
Journal:  Sports Med       Date:  2009       Impact factor: 11.136

9.  Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults.

Authors:  Lei Li; C-Y Oliver Chen; Giancarlo Aldini; Elizabeth J Johnson; Helen Rasmussen; Yasukazu Yoshida; Etsuo Niki; Jeffrey B Blumberg; Robert M Russell; Kyung-Jin Yeum
Journal:  J Nutr Biochem       Date:  2009-05-15       Impact factor: 6.048

10.  Ascorbic acid protects against restraint stress-induced memory deficits in Wistar rats.

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Journal:  Clinics (Sao Paulo)       Date:  2009       Impact factor: 2.365

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