Literature DB >> 33040057

Efficacy of Low-Carbohydrate Ketogenic Diet in the Treatment of Type 2 Diabetes.

Hussain M Dashti1, Thazhumpal C Mathew2, Naji S Al-Zaid3.   

Abstract

Low-carbohydrate ketogenic diet (LCKD), originally used as a treatment for childhood epilepsy is currently gaining acceptance as a nutritional therapy for obesity and type 2 diabetes. In addition, this diet has a positive effect on body weight, blood glucose level, glycosylated hemoglobin, plasma lipid profile, and neurological disorders. This review focuses on the therapeutic effectiveness, negative effects, and the rationale of using LCKD for the treatment of type 2 diabetes. It is shown that LCKD contributes to the reduction in the intake of insulin and oral antidiabetic drugs in patients with type 2 diabetes. Furthermore, the data presented in this review reveal the efficacy and cost-effectiveness of LCKD in the management of type 2 diabetes.
© 2020 The Author(s) Published by S. Karger AG, Basel.

Entities:  

Keywords:  HbA1c; Low-carbohydrate ketogenic diet; Obesity; Type 2 diabetes

Mesh:

Substances:

Year:  2020        PMID: 33040057      PMCID: PMC8280429          DOI: 10.1159/000512142

Source DB:  PubMed          Journal:  Med Princ Pract        ISSN: 1011-7571            Impact factor:   1.927


  79 in total

Review 1.  A review of low-carbohydrate ketogenic diets.

Authors:  Eric C Westman; John Mavropoulos; William S Yancy; Jeff S Volek
Journal:  Curr Atheroscler Rep       Date:  2003-11       Impact factor: 5.113

Review 2.  Diabetic retinopathy.

Authors:  Donald S Fong; Lloyd P Aiello; Frederick L Ferris; Ronald Klein
Journal:  Diabetes Care       Date:  2004-10       Impact factor: 19.112

Review 3.  Mitochondrial energetics and therapeutics.

Authors:  Douglas C Wallace; Weiwei Fan; Vincent Procaccio
Journal:  Annu Rev Pathol       Date:  2010       Impact factor: 23.472

Review 4.  Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials.

Authors:  Nassib Bezerra Bueno; Ingrid Sofia Vieira de Melo; Suzana Lima de Oliveira; Terezinha da Rocha Ataide
Journal:  Br J Nutr       Date:  2013-05-07       Impact factor: 3.718

Review 5.  The regulation of the release of ketone bodies by the liver.

Authors:  H A Krebs
Journal:  Adv Enzyme Regul       Date:  1966

Review 6.  Clinical aspects of the ketogenic diet.

Authors:  Adam L Hartman; Eileen P G Vining
Journal:  Epilepsia       Date:  2007-01       Impact factor: 5.864

Review 7.  The prevention and treatment of metabolic syndrome and high-risk obesity.

Authors:  Behzad Molavi; Neda Rasouli; Philip A Kern
Journal:  Curr Opin Cardiol       Date:  2006-09       Impact factor: 2.161

8.  The human metabolic response to chronic ketosis without caloric restriction: physical and biochemical adaptation.

Authors:  S D Phinney; B R Bistrian; R R Wolfe; G L Blackburn
Journal:  Metabolism       Date:  1983-08       Impact factor: 8.694

9.  Beneficial effects of ketogenic diet in obese diabetic subjects.

Authors:  Hussein M Dashti; Thazhumpal C Mathew; Mousa Khadada; Mahdi Al-Mousawi; Husain Talib; Sami K Asfar; Abdulla I Behbahani; Naji S Al-Zaid
Journal:  Mol Cell Biochem       Date:  2007-04-20       Impact factor: 3.396

10.  Reversal of diabetic nephropathy by a ketogenic diet.

Authors:  Michal M Poplawski; Jason W Mastaitis; Fumiko Isoda; Fabrizio Grosjean; Feng Zheng; Charles V Mobbs
Journal:  PLoS One       Date:  2011-04-20       Impact factor: 3.240

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  3 in total

Review 1.  Efficacy of Ketogenic Diets on Type 2 Diabetes: a Systematic Review.

Authors:  Delphine Tinguely; Justine Gross; Christophe Kosinski
Journal:  Curr Diab Rep       Date:  2021-08-27       Impact factor: 4.810

2.  Can older patients adopt and maintain a ketogenic diet? An observational study in support of clinical trials in older patients.

Authors:  Yahya Almodallal; Kathryn Cook; Lisa M Lammert; Minji Lee; Jennifer G Le-Rademacher; Aminah Jatoi
Journal:  Medicine (Baltimore)       Date:  2021-11-24       Impact factor: 1.817

3.  β-Hydroxybutyrate upregulates FGF21 expression through inhibition of histone deacetylases in hepatocytes.

Authors:  Aili Yan; Yanyan Zhao; Lijun Zhang; Xiangyan Liang; Xiaochun Zhang; Fenli Liang; Shen Nian; Xinhua Li; Zhuo Sun; Ke Li; Yu-Feng Zhao
Journal:  Open Life Sci       Date:  2022-08-10       Impact factor: 1.311

  3 in total

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