| Literature DB >> 33037976 |
Abstract
In the last 15 years, a debate has emerged about the validity of the famous Hodgkin-Huxley model for nerve impulse. Mechanical models have been proposed. This note reviews the experimental properties of the nerve impulse and discusses the proposed alternatives. The experimental data, which rule out some of the alternative suggestions, show that while the Hodgkin-Huxley model may not be complete, it nevertheless includes essential features that should not be overlooked in the attempts made to improve, or supersede, it.Keywords: Axon; Hodgkin-Huxley model; Nerve cell; Nerve impulse
Year: 2020 PMID: 33037976 PMCID: PMC7719126 DOI: 10.1007/s10867-020-09557-2
Source DB: PubMed Journal: J Biol Phys ISSN: 0092-0606 Impact factor: 1.365