Literature DB >> 33037395

Integrin-targeted therapies branch out.

Megan Cully.   

Abstract

Year:  2020        PMID： 33037395     DOI： 10.1038/d41573-020-00180-3

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  7 in total

1.  The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo.

Authors:  S de Frutos; M Griera; M Hatem-Vaquero; S Campillo; E Gutiérrez-Calabres; D García-Ayuso; M Pardo; L Calleros; M Rodríguez-Puyol; D Rodríguez-Puyol
Journal:  Cell Biosci       Date:  2022-01-28       Impact factor: 7.133

Review 2.  Role of Integrins in Modulating Smooth Muscle Cell Plasticity and Vascular Remodeling: From Expression to Therapeutic Implications.

Authors:  Manish Jain; Anil K Chauhan
Journal:  Cells       Date:  2022-02-13       Impact factor: 6.600

3.  Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells.

Authors:  Shiv Ram Krishn; Vaughn Garcia; Nicole M Naranjo; Fabio Quaglia; Christopher D Shields; Maisha A Harris; Andrew V Kossenkov; Qin Liu; Eva Corey; Dario C Altieri; Lucia R Languino
Journal:  Cancer Biol Ther       Date:  2022-12-31       Impact factor: 4.875

4.  Research-Based Product Innovation to Address Critical Unmet Needs of Patients with Inflammatory Bowel Diseases.

Authors:  Gerard Honig; Paul B Larkin; Caren Heller; Andrés Hurtado-Lorenzo
Journal:  Inflamm Bowel Dis       Date:  2021-11-15       Impact factor: 5.325

5.  CRISPR-mediated activation of autism gene Itgb3 restores cortical network excitability via mGluR5 signaling.

Authors:  Fanny Jaudon; Agnes Thalhammer; Lorena Zentilin; Lorenzo A Cingolani
Journal:  Mol Ther Nucleic Acids       Date:  2022-07-20       Impact factor: 10.183

6.  The glycocalyx affects the mechanotransductive perception of the topographical microenvironment.

Authors:  Matteo Chighizola; Alessandro Podestà; Carsten Schulte; Tania Dini; Stefania Marcotti; Mirko D'Urso; Claudio Piazzoni; Francesca Borghi; Anita Previdi; Laura Ceriani; Claudia Folliero; Brian Stramer; Cristina Lenardi; Paolo Milani
Journal:  J Nanobiotechnology       Date:  2022-09-19       Impact factor: 9.429

7.  Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis.

Authors:  Xiaochao Tan; Priyam Banerjee; Xin Liu; Jiang Yu; Sieun Lee; Young-Ho Ahn; Chad J Creighton; Jonathan M Kurie
Journal:  JCI Insight       Date:  2022-01-11
  7 in total

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