Laura E Miller1, Chris DeRienzo2, P Brian Smith1,3, Carl Bose4, Reese H Clark5, C Michael Cotten1, Daniel K Benjamin6, Chi D Hornik1,3, Rachel G Greenberg7,8. 1. Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA. 2. Department of Medicine, Division of Population Health, Stanford University, Stanford, CA, USA. 3. Duke Clinical Research Institute, Durham, NC, USA. 4. Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 5. Pediatrix Medical Group Inc, Sunrise, FL, USA. 6. Clemson University, Clemson, SC, USA. 7. Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA. rachel.greenberg@duke.edu. 8. Duke Clinical Research Institute, Durham, NC, USA. rachel.greenberg@duke.edu.
Abstract
OBJECTIVE: Determine the associations between neonatal intensive care unit (NICU) medication safety practices, laboratory-based adverse events (lab-AEs), and death. STUDY DESIGN: We combined data from a 2016 survey of Pediatrix NICUs on use of medication safety practices with 2014-2016 infant data. We grouped NICUs based on the number of safety practices used (≤5, 6-7, and 8-10) and evaluated the association between the number of safety practices used and lab-AEs and deaths using logistic regressions. RESULTS: Of the 94 NICUs included, 17% used ≤5 medication safety practices, 51% used 6-7, and 32% used 8-10. NICUs with more safety practices did not have a difference in lab-AEs or death. CONCLUSION: In this cohort, the use of more medication safety practices was not associated with fewer lab-AEs or decreased death.
OBJECTIVE: Determine the associations between neonatal intensive care unit (NICU) medication safety practices, laboratory-based adverse events (lab-AEs), and death. STUDY DESIGN: We combined data from a 2016 survey of Pediatrix NICUs on use of medication safety practices with 2014-2016 infant data. We grouped NICUs based on the number of safety practices used (≤5, 6-7, and 8-10) and evaluated the association between the number of safety practices used and lab-AEs and deaths using logistic regressions. RESULTS: Of the 94 NICUs included, 17% used ≤5 medication safety practices, 51% used 6-7, and 32% used 8-10. NICUs with more safety practices did not have a difference in lab-AEs or death. CONCLUSION: In this cohort, the use of more medication safety practices was not associated with fewer lab-AEs or decreased death.
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