Literature DB >> 3303228

Pathology of growth hormone-producing tumors of the human pituitary.

K Kovacs, E Horvath.   

Abstract

This paper reviews the morphologic features of growth hormone-producing tumors of the human pituitary. These tumors are associated with elevated blood growth hormone levels and acromegaly or gigantism and can be classified into the following morphologically distinct entities by the combined application of histology, immunocytology, and electron microscopy: densely granulated growth hormone cell adenoma; sparsely granulated growth hormone cell adenoma; mixed growth hormone cell- prolactin cell-adenoma; acidophil stem cell adenoma; mammosomatotroph cell adenoma; growth hormone cell carcinoma; plurihormonal adenoma with growth hormone production.

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Year:  1986        PMID： 3303228

Source DB:  PubMed          Journal:  Semin Diagn Pathol        ISSN： 0740-2570            Impact factor:   3.464


  17 in total

Review 1.  Human pituitary adenomas. Recent advances in morphological studies.

Authors:  G Giannattasio; M Bassetti
Journal:  J Endocrinol Invest       Date:  1990-05       Impact factor: 4.256

2.  Cytokeratin distribution and functional properties of growth hormone-producing pituitary adenomas.

Authors:  Toshiaki Sano; Shozo Yamada; Takashi Hi Rose; Kazuo Hizawa
Journal:  Endocr Pathol       Date:  1994-06       Impact factor: 3.943

3.  Immunohistochemical colocalization of growth hormone (GH) and alpha subunit in human GH secreting pituitary adenomas.

Authors:  R Y Osamura; K Watanabe
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

4.  Factors predicting pituitary adenoma invasiveness in acromegalic patients.

Authors:  A Rieger; N G Rainov; H Ebel; L Sanchin; K Shibib; C Helfrich; O Hoffmann; W Burkert
Journal:  Neurosurg Rev       Date:  1997       Impact factor: 3.042

5.  Silent somatotroph adenomas of the human pituitary. A morphologic study of three cases including immunocytochemistry, electron microscopy, in vitro examination, and in situ hybridization.

Authors:  K Kovacs; R Lloyd; E Horvath; S L Asa; L Stefaneanu; D W Killinger; H S Smyth
Journal:  Am J Pathol       Date:  1989-02       Impact factor: 4.307

6.  Effects of growth hormone-releasing hormone (GHRH) on densely granulated somatotroph adenomas and sparsely granulated somatotroph adenomas in vitro: a morphological and functional investigation.

Authors:  S Kawakita; S L Asa; K Kovacs
Journal:  J Endocrinol Invest       Date:  1989 Jul-Aug       Impact factor: 4.256

7.  Growth hormone (GH) and prolactin (PRL) gene expression and immunoreactivity in GH- and PRL-producing human pituitary adenomas.

Authors:  J Li; L Stefaneanu; K Kovacs; E Horvath; H S Smyth
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1993

Review 8.  Mechanisms for pituitary tumorigenesis: the plastic pituitary.

Authors:  Shlomo Melmed
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808

Review 9.  Keratin expression in endocrine organs and their neoplasms.

Authors:  Peiguo G Chu; Sean K Lau; Lawrence M Weiss
Journal:  Endocr Pathol       Date:  2009       Impact factor: 3.943

10.  Immunohistochemistry as a predictor of clinical outcome in patients given postoperative radiation for subtotally resected pituitary adenomas.

Authors:  J J Kovalic; G Mazoujian; D W McKeel; B B Fineberg; P W Grigsby
Journal:  J Neurooncol       Date:  1993-06       Impact factor: 4.130
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