Adel Alothman1, Abdulhakeem Al Thaqafi2, Adel Al Ansary3, Ahmed Zikri4, Akram Fayed5, Faryal Khamis6, Jameela Al Salman7, Laila Al Dabal8, Natasha Khalife9, Tariq AlMusawi10, Wadha Alfouzan11, Said El Zein12, Ramy Kotb13, Yasser Ghoneim9, Souha S Kanj14. 1. National Guard Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia. 2. King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, National Guard Health Affairs, Jeddah, Saudi Arabia. 3. Ainshams University Hospital, Cairo, Egypt. 4. King Fahad Specialist Hospital, Dammam, Saudi Arabia. 5. Alexandria University Hospitals, Alexandria, Egypt. 6. Royal Hospital, Muscat, Oman. 7. Salmaniya Medical Complex, Manama, Bahrain. 8. Rashid Hospital, Dubai, United Arab Emirates. 9. Real-World Evidence, IQVIA, Dubai, United Arab Emirates. 10. King Fahd Hospital of the University, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia. 11. Microbiology Department, Faculty of Medicine, Kuwait University, Farwaniya Hospital, Kuwait City, Kuwait. 12. American University of Beirut (AUB), Beirut, Lebanon. 13. Pfizer, Dubai, United Arab Emirates. Electronic address: Ramy.e.kotb@pfizer.com. 14. American University of Beirut (AUB), Beirut, Lebanon. Electronic address: sk11@aub.edu.lb.
Abstract
OBJECTIVES: Community-acquired (CAIs) and healthcare-associated (HAIs) infections are associated with significant morbidity and mortality. Data related to the epidemiology of these infections in the Middle East is scarce. The aim of this study is to estimate the prevalence of infections and antimicrobial use in the acute hospital setting in this region. METHODS: A multicentre Point-Prevalence Survey was conducted in seven Middle Eastern countries: Egypt, Kingdom of Saudi Arabia, United Arab Emirates, Lebanon, Oman, Kuwait and Bahrain. Data were collected by the infection control and infectious diseases teams of the respective hospitals. Study surveys were completed in one day (03 April 2018). RESULTS: The overall point prevalence of infection was 28.3%; HAI and CAI point prevalence was 11.2% and 16.8%, respectively. The majority of patients with an infection (98.2%) were receiving antimicrobial therapy. There were high levels of resistance to antimicrobials among Acinetobacter baumannii, Enterobacter cloacae, Klebsiella pneumoniae and other Klebsiella sp. CONCLUSIONS: Our findings indicate that the point prevalence of both HAI and CAI is high in a sample of Middle Eastern countries. These findings along with the increased use of antimicrobials represent a significant public health problem in the region; particularly in light of the growing regional antimicrobial resistance.
OBJECTIVES: Community-acquired (CAIs) and healthcare-associated (HAIs) infections are associated with significant morbidity and mortality. Data related to the epidemiology of these infections in the Middle East is scarce. The aim of this study is to estimate the prevalence of infections and antimicrobial use in the acute hospital setting in this region. METHODS: A multicentre Point-Prevalence Survey was conducted in seven Middle Eastern countries: Egypt, Kingdom of Saudi Arabia, United Arab Emirates, Lebanon, Oman, Kuwait and Bahrain. Data were collected by the infection control and infectious diseases teams of the respective hospitals. Study surveys were completed in one day (03 April 2018). RESULTS: The overall point prevalence of infection was 28.3%; HAI and CAI point prevalence was 11.2% and 16.8%, respectively. The majority of patients with an infection (98.2%) were receiving antimicrobial therapy. There were high levels of resistance to antimicrobials among Acinetobacter baumannii, Enterobacter cloacae, Klebsiella pneumoniae and other Klebsiella sp. CONCLUSIONS: Our findings indicate that the point prevalence of both HAI and CAI is high in a sample of Middle Eastern countries. These findings along with the increased use of antimicrobials represent a significant public health problem in the region; particularly in light of the growing regional antimicrobial resistance.
Authors: Zainab Said Al-Hashimy; Barbara R Conway; Mubarak Al-Yaqoobi; Faryal Khamis; Ghalib Zahran Al Mawali; Aisha Mahad Al Maashani; Yaqoob Said Al Hadhrami; Said Salim Al Alawi; Mohammed Said Al Mamari; William J Lattyak; Elizabeth A Lattyak; Motasem Aldiab; Ian Gould; José-María López-Lozano; Mamoon A Aldeyab Journal: Antibiotics (Basel) Date: 2022-06-07