Nazimah Ab Mumin 1 , Kartini Rahmat 1 , Marlina Tanty Ramli Hamid 1 , Wei Lin Ng 1 , Wai Yee Chan 1 , Xin Ying Cheah 2 , Mee Hoong See 3 , Cheng Har Yip 4 . Show Affiliations »
Abstract
BACKGROUND: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. CASE REPORT: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy. DISCUSSION: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement. CONCLUSION: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
BACKGROUND: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. CASE REPORT: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain , she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma . The diagnosis was confirmed after biopsy and she underwent mastectomy. DISCUSSION: Literature review on imaging findings of breast angiosarcoma , especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement. CONCLUSION: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma , and hence, should be offered sooner to prevent diagnostic delay. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Entities: Disease
Keywords:
Breast angiosarcoma; breast cancer.; digital breast tomosynthesis(zzm321990DBT); magnetic resonance imaging (MRI); primary breast angiosarcoma; ultrasound elastography
Year: 2021
PMID: 33030134 DOI: 10.2174/1573405616666201007161119
Source DB: PubMed Journal: Curr Med Imaging