Literature DB >> 3302929

Liposomes in treatment of infectious diseases.

F Emmen, G Storm.   

Abstract

In reviewing the literature about the potential of liposomes in the therapy of infections caused by protozoa, bacteria, fungi and viruses, it can be concluded that liposomal encapsulation may improve the therapeutic index of anti-infectious drugs. The improved therapeutic index may be a result of a reduction in drug toxicity and/or an enhanced drug delivery at the intracellular site of infection. Furthermore, attention is paid to the therapeutic utility of liposome-encapsulated immunomodulators in treatment of infections.

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Year:  1987        PMID: 3302929     DOI: 10.1007/BF01967536

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN: 0167-6555


  63 in total

1.  Interaction between phagocytes and pathogenic microorganisms.

Authors:  E SUTER
Journal:  Bacteriol Rev       Date:  1956-06

2.  Effect of liposome-entrapped ampicillin on survival of Listeria monocytogenes in murine peritoneal macrophages.

Authors:  I A Bakker-Woudenberg; A F Lokerse; J C Vink-van den Berg; F H Roerdink; M F Michel
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

3.  Effect of liposomal amphotericin B on murine macrophages and lymphocytes.

Authors:  R T Mehta; K Mehta; G Lopez-Berestein; R L Juliano
Journal:  Infect Immun       Date:  1985-02       Impact factor: 3.441

4.  Proceedings: Causes of death in cancer patients.

Authors:  J Inagaki; V Rodriguez; G P Bodey
Journal:  Cancer       Date:  1974-02       Impact factor: 6.860

5.  Diffusion of univalent ions across the lamellae of swollen phospholipids.

Authors:  A D Bangham; M M Standish; J C Watkins
Journal:  J Mol Biol       Date:  1965-08       Impact factor: 5.469

6.  Mechanisms of acquired resistance to Pasteurella multocida infection: a review.

Authors:  F M Collins
Journal:  Cornell Vet       Date:  1977-01

7.  Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro.

Authors:  J Dijkstra; M Van Galen; G L Scherphof
Journal:  Biochim Biophys Acta       Date:  1984-05-22

8.  Treatment and prophylaxis of disseminated infection due to Candida albicans in mice with liposome-encapsulated amphotericin B.

Authors:  G Lopez-Berestein; R Mehta; R L Hopfer; K Mills; L Kasi; K Mehta; V Fainstein; M Luna; E M Hersh; R Juliano
Journal:  J Infect Dis       Date:  1983-05       Impact factor: 5.226

9.  The role of the Kupffer cell in the infection of rodents by sporozoites of Plasmodium: uptake of sporozoites by perfused liver and the establishment of infection in vivo.

Authors:  R E Sihden; J E Smith
Journal:  Acta Trop       Date:  1982-03       Impact factor: 3.112

10.  Liposomal amphotericin B for the treatment of systemic fungal infections in patients with cancer: a preliminary study.

Authors:  G Lopez-Berestein; V Fainstein; R Hopfer; K Mehta; M P Sullivan; M Keating; M G Rosenblum; R Mehta; M Luna; E M Hersh
Journal:  J Infect Dis       Date:  1985-04       Impact factor: 5.226

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  5 in total

1.  Enhanced effect of liposome-encapsulated amikacin on Mycobacterium avium-M. intracellulare complex infection in beige mice.

Authors:  N Düzgüneş; V K Perumal; L Kesavalu; J A Goldstein; R J Debs; P R Gangadharam
Journal:  Antimicrob Agents Chemother       Date:  1988-09       Impact factor: 5.191

Review 2.  Liposomes as carriers of antimicrobial agents or immunomodulatory agents in the treatment of infections.

Authors:  I A Bakker-Woudenberg; A F Lokerse; M T ten Kate; P M Melissen; W van Vianen; E W van Etten
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993       Impact factor: 3.267

3.  Liposome encapsulation of clofazimine reduces toxicity in vitro and in vivo and improves therapeutic efficacy in the beige mouse model of disseminated Mycobacterium avium-M. intracellulare complex infection.

Authors:  R T Mehta
Journal:  Antimicrob Agents Chemother       Date:  1996-08       Impact factor: 5.191

4.  Effect of lipid composition on activity of liposome-entrapped ampicillin against intracellular Listeria monocytogenes.

Authors:  I A Bakker-Woudenberg; A F Lokerse; F H Roerdink
Journal:  Antimicrob Agents Chemother       Date:  1988-10       Impact factor: 5.191

5.  Chloroquine blood levels after administration of the liposome-encapsulated drug in relation to therapy of murine malaria.

Authors:  P A Peeters; K de Leest; W M Eling; D J Crommelin
Journal:  Pharm Res       Date:  1989-09       Impact factor: 4.200

  5 in total

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