Literature DB >> 33027349

Risk factors associated with delay in diagnosis and mortality in patients with COVID-19 in the city of Rio de Janeiro, Brazil.

Alexandre de Fátima Cobre1, Beatriz Böger1, Mariana Millan Fachi1, Raquel de Oliveira Vilhena1, Eric Luiz Domingos1, Fernanda Stumpf Tonin1, Roberto Pontarolo1.   

Abstract

We investigated the predictors of delay in the diagnosis and mortality of patients with COVID-19 in Rio de Janeiro, Brazil. A cohort of 3,656 patients were evaluated (Feb-Apr 2020) and patients' sociodemographic characteristics, and social development index (SDI) were used as determinant factors of diagnosis delays and mortality. Kaplan-Meier survival analyses, time-dependent Cox regression models, and multivariate logistic regression analyses were conducted. The median time from symptoms onset to diagnosis was eight days (interquartile range [IQR] 7.23-8.99 days). Half of the patients recovered during the evaluated period, and 8.3% died. Mortality rates were higher in men. Delays in diagnosis were associated with male gender (p = 0.015) and patients living in low SDI areas (p < 0.001). The age groups statistically associated with death were: 70-79 years, 80-89 years, and 90-99 years. Delays to diagnosis greater than eight days were also risk factors for death. Delays in diagnosis and risk factors for death from COVID-19 were associated with male gender, age under 60 years, and patients living in regions with lower SDI. Delays superior to eight days to diagnosis increased mortality rates.

Entities:  

Mesh:

Year:  2020        PMID: 33027349     DOI: 10.1590/1413-812320202510.2.26882020

Source DB:  PubMed          Journal:  Cien Saude Colet        ISSN: 1413-8123


  10 in total

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  10 in total

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