Literature DB >> 3302545

Immunomodulatory activity of an aqueous extract of Azadirachta indica stem bark.

J M van der Nat, J P Klerx, H van Dijk, K T de Silva, R P Labadie.   

Abstract

The interference of an aqueous extract of the stem bark of Azadirachta indica with different parts of the human immune system was investigated. The extract showed strong anticomplementary effects which were dose-and time-dependent and most pronounced in the classical complement pathway assay. Moreover, a dose-dependent decrease in the chemiluminescence of polymorphonuclear leukocytes was observed and a dose-dependent increase in the production of migration inhibition factor by lymphocytes.

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Year:  1987        PMID： 3302545     DOI： 10.1016/0378-8741(87)90036-5

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  9 in total

1.  Inhibition of chemiluminescence and chemotactic activity of phagocytes in vitro by the extracts of selected medicinal plants.

Authors:  Ibrahim Jantan; Nurul Hikmah Harun; Abdi Wira Septama; Shahnaz Murad; M A Mesaik
Journal:  J Nat Med       Date:  2010-12-25       Impact factor: 2.343

2.  Teratogenic effects of ethanol extract of Curcuma mangga Val. rhizomes in wistar rats.

Authors:  Krisna Sandra Amalia Tarigan; Sri Yuliasmi
Journal:  Toxicol Res       Date:  2021-01-22

Review 3.  Azadirachta indica: A herbal panacea in dentistry - An update.

Authors:  T Lakshmi; Vidya Krishnan; R Rajendran; N Madhusudhanan
Journal:  Pharmacogn Rev       Date:  2015 Jan-Jun

4.  Inhibitory effects of compounds from Phyllanthus amarus on nitric oxide production, lymphocyte proliferation, and cytokine release from phagocytes.

Authors:  Ibrahim Jantan; Menaga Ilangkovan; Khairana Husain; Kok Meng Chan
Journal:  Drug Des Devel Ther       Date:  2016-06-09       Impact factor: 4.162

5.  Immunomodulatory Effect of Gymnema sylvestre (R.Br.) Leaf Extract: An In Vitro Study in Rat Model.

Authors:  Vineet Kumar Singh; Padmanabh Dwivedi; B R Chaudhary; Ramesh Singh
Journal:  PLoS One       Date:  2015-10-16       Impact factor: 3.240

6.  Wound Healing Activity of Azadirachta indica A. Juss Stem Bark in Mice.

Authors:  Preeti Maan; Kuldeep Singh Yadav; Narayan Prasad Yadav
Journal:  Pharmacogn Mag       Date:  2017-07-11       Impact factor: 1.085

7.  Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro.

Authors:  Saurav Kumar; Vaishali Mulchandani; Jayasri Das Sarma
Journal:  BMC Complement Med Ther       Date:  2022-09-10

8.  Inhibitory Effects of Standardized Extracts of Phyllanthus amarus and Phyllanthus urinaria and Their Marker Compounds on Phagocytic Activity of Human Neutrophils.

Authors:  Menaga Ilangkovan; Ibrahim Jantan; Hazni Falina Mohamad; Khairana Husain; Amirul Faiz Abdul Razak
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-02       Impact factor: 2.629

9.  Metabolomic Profiling and Immunomodulatory Activity of a Polyherbal Combination in Cyclophosphamide-Induced Immunosuppressed Mice.

Authors:  Sultan Zahiruddin; Abida Parveen; Washim Khan; Mohammad Ibrahim; Muzamil Y Want; Rabea Parveen; Sayeed Ahmad
Journal:  Front Pharmacol       Date:  2022-01-03       Impact factor: 5.810
  9 in total

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